UniProt Q2U1F3
Leucine aminopeptidase A (Q2U1F3)
Leucine aminopeptidase A (UniProt Q2U1F3), EC 3.4.11.-: 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q2U1F3
- Protein
- Leucine aminopeptidase A
- EC
- 3.4.11.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 4 · 1 record with a druggable one
Structures
7 records of Q2U1F3 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ZEP | Flavourzyme Leucine Aminopeptidase A proenzyme | x-ray diffraction | A | NAG, ZN, CL | 2 (best 0.65) |
| 6ZEP | Flavourzyme leucine aminopeptidase a proenzyme | x-ray diffraction | A | NAG, ZN, CL | — |
| 6ZEQ | Aspergillus oryzae Leucine Aminopeptidase A mature enzyme | x-ray diffraction | A | NAG, ZN, CL, SO4 | 1 (best 0.37) |
| 6ZEQ | Aspergillus oryzae leucine aminopeptidase a mature enzyme | x-ray diffraction | A | NAG, ZN, CL, SO4 | — |
| 7OEZ | Leucine Aminopeptidase A mature enzyme in a complex with leucine | x-ray diffraction | A | NAG, SO4, ZN, CL, LEU | 1 (best 0.45) |
| 7OEZ | Leucine aminopeptidase a mature enzyme in a complex with leucine | x-ray diffraction | A | NAG, SO4, ZN, CL | — |
| Q2U1F3 | AlphaFold monomer V2.0 prediction for leucine aminopeptidase a (Q2U1F3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7OEZ chain A against the predicted model Q2U1F3: TM-score 0.99, RMSD 0.54 Å
- 6ZEQ chain A against the predicted model Q2U1F3: TM-score 0.99, RMSD 0.54 Å
- 6ZEQ chain A against the predicted model Q2U1F3: TM-score 0.99, RMSD 0.54 Å
- 6ZEP chain A against the predicted model Q2U1F3: TM-score 0.99, RMSD 0.60 Å
- 6ZEP chain A against the predicted model Q2U1F3: TM-score 0.99, RMSD 0.60 Å
- 7OEZ chain A against the predicted model Q2U1F3: TM-score 0.99, RMSD 0.54 Å
Elsewhere
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