UniProt Q2G0N1
Elongation factor G (Q2G0N1)
Elongation factor G (UniProt Q2G0N1): 3 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q2G0N1
- Protein
- Elongation factor G
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 1 · 1 record with a druggable one
Structures
4 records of Q2G0N1 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8P2F | Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane… | electron microscopy | E | GDP, MG, WUX | 1 (best 0.84) |
| 8P2G | Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane… | electron microscopy | E | GDP, MG, WUX | — |
| 8P2H | Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid with a tRNA in… | electron microscopy | E | GDP, MG, FUA | — |
| Q2G0N1 | AlphaFold monomer V2.0 prediction for elongation factor G (Q2G0N1) | predicted | A | — | — |
Ligands
- GDP · Guanosine-5'-diphosphate · in 3 records
- MG · Magnesium ion · in 3 records
- WUX · 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid · in 2 records
- FUA · Fusidic acid · in 1 record
Experiment against prediction
- 8P2F chain E against the predicted model Q2G0N1: TM-score 0.94, RMSD 2.41 Å
- 8P2H chain E against the predicted model Q2G0N1: TM-score 0.94, RMSD 2.43 Å
- 8P2G chain E against the predicted model Q2G0N1: TM-score 0.94, RMSD 2.46 Å
Elsewhere
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