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Ligand · WUX

WUX · 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid

WUX, 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid…

Component
WUX
Formula
C33 H54 O6
Class
ligand
Structures
2
PDB entries
2

Binding sites

WUX in 2 structures; the first of them:

  • 8P2F · Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid… · WUX E703 · binds A2689, G2690, ILE63, ASP81, THR82, PRO83, HIS85, PHE88 and 9 more
  • 8P2G · Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid… · WUX E703 · binds A2689, G2690, ASP81, THR82, PRO83, HIS85, PHE88, GLU91 and 8 more

Residues it binds most

ASP 2, GLU 2, HIS 2, LEU 2, ILE 2, A 2, ARG 2, G 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • GDP · Guanosine-5'-diphosphate
  • PUT · 1,4-diaminobutane
  • SPD · Spermidine
  • MG · Magnesium ion
  • ZN · Zinc ion
  • K · Potassium ion

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