UniProt Q25252
Carboxylic ester hydrolase (Q25252)
Carboxylic ester hydrolase (UniProt Q25252), EC 3.1.1.-: 53 experimental structures on GenesisL1, 7 ligands bound, 17 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q25252
- Protein
- Carboxylic ester hydrolase
- EC
- 3.1.1.-
- Experimental structures
- 53
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 17 · 5 records with a druggable one
Structures
53 records of Q25252 in the MolNFT archive: 53 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4FNG | The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina | x-ray diffraction | A | — | — |
| 4FNG | The alpha-esterase-7 carboxylesterase, E3, from the blowfly lucilia cuprina | x-ray diffraction | A | — | — |
| 4FNM | The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina | x-ray diffraction | A | — | — |
| 4FNM | The alpha-esterase-7 carboxylesterase, E3, from the blowfly lucilia cuprina | x-ray diffraction | A | — | — |
| 4QWM | KINETIC CRYSTALLOGRAPHY of ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 1.85… | x-ray diffraction | A | — | — |
| 4QWM | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 1.85… | x-ray diffraction | A | — | — |
| 4UBI | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 3.70… | x-ray diffraction | A | — | — |
| 4UBI | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 3.70… | x-ray diffraction | A | — | — |
| 4UBJ | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 5.55… | x-ray diffraction | A | — | — |
| 4UBJ | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 5.55… | x-ray diffraction | A | — | — |
| 4UBK | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 7.40… | x-ray diffraction | A | — | — |
| 4UBK | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 7.40… | x-ray diffraction | A | — | — |
| 4UBL | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 9.26… | x-ray diffraction | A | — | — |
| 4UBL | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 9.26… | x-ray diffraction | A | — | — |
| 4UBM | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE… | x-ray diffraction | A | — | — |
| 4UBM | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose… | x-ray diffraction | A | — | — |
| 4UBN | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 1.85… | x-ray diffraction | A | — | — |
| 4UBN | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 1.85… | x-ray diffraction | A | — | — |
| 4UBO | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 3.70… | x-ray diffraction | A | — | — |
| 4UBO | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 3.70… | x-ray diffraction | A | — | — |
| 4W1P | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 5.54… | x-ray diffraction | A | — | — |
| 4W1P | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 5.54… | x-ray diffraction | A | — | — |
| 4W1Q | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 7.39… | x-ray diffraction | A | — | — |
| 4W1Q | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 7.39… | x-ray diffraction | A | — | — |
| 4W1R | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 9.24… | x-ray diffraction | A | — | — |
| 4W1R | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose 9.24… | x-ray diffraction | A | — | — |
| 4W1S | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE… | x-ray diffraction | A | — | — |
| 4W1S | Kinetic crystallography of ALPHA_E7-carboxylesterse from lucilla cuprina - absorbed X-ray dose… | x-ray diffraction | A | — | — |
| 5C8V | Lucilia cuprina alpha esterase 7: Gly137Asp | x-ray diffraction | A | — | 3 (best 0.71) |
| 5C8V | Lucilia cuprina alpha esterase 7: GLY137ASP | x-ray diffraction | A | — | — |
| 5CH3 | E3 alpha-esterase-7 carboxylesterase | x-ray diffraction | A | — | — |
| 5CH5 | E3 alpha-esterase-7 carboxylesterase | x-ray diffraction | A | — | — |
| 5IKX | Crystal structure of the alpha-esterase-7 carboxyl esterase (dimer), E3, from Lucilia cuprina | x-ray diffraction | A, B | — | — |
| 5IKX | Crystal structure of the alpha-esterase-7 carboxyl esterase (dimer), E3, from lucilia cuprina | x-ray diffraction | A, B | — | — |
| 5IVD | The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina: apo-enzyme qFit… | x-ray diffraction | A | — | 4 (best 0.73) |
| 5IVD | The alpha-esterase-7 carboxylesterase, E3, from the blowfly lucilia cuprina: apo-enzyme qfit… | x-ray diffraction | A | — | — |
| 5IVH | The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina: apo-enzyme ensemble… | x-ray diffraction | A | — | — |
| 5IVH | The alpha-esterase-7 carboxylesterase, E3, from the blowfly lucilia cuprina: apo-enzyme ensemble… | x-ray diffraction | A | — | — |
| 5IVI | The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina: phosphorylated enzyme… | x-ray diffraction | A | DPF | 4 (best 0.74) |
| 5IVI | The alpha-esterase-7 carboxylesterase, E3, from the blowfly lucilia cuprina: phosphorylated enzyme… | x-ray diffraction | A | — | — |
| 5IVK | The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina: phosphorylated-enzyme… | x-ray diffraction | A | DPF | — |
| 5IVK | The alpha-esterase-7 carboxylesterase, E3, from the blowfly lucilia cuprina: phosphorylated-enzyme… | x-ray diffraction | A | — | — |
| 5TYJ | Alpha-esterase-7 in complex with (3-bromo-5-PHENOXYLPHENYL)BORONIC acid | x-ray diffraction | A | 7ND | — |
| 5TYK | alpha-esterase-7 in complex with 3-chloro-4-[(2-fluorophenyl)methoxy]phenylborinic acid | x-ray diffraction | A | 7N4 | — |
| 5TYK | Alpha-esterase-7 in complex with 3-chloro-4-[(2-fluorophenyl) METHOXY]PHENYLBORINIC acid | x-ray diffraction | A | 7N4 | — |
| 5TYL | alpha-esterase-7 in complex with naphthalen-2-ylboronic acid | x-ray diffraction | A | 7N7 | 3 (best 0.75) |
| 5TYL | Alpha-esterase-7 in complex with naphthalen-2-ylboronic acid | x-ray diffraction | A | 7N7 | — |
| 5TYM | Alpha-esterase-7 in complex with [3-bromo-5-(pyrrolidin-1-yl) PHENYL]BORINIC acid | x-ray diffraction | A | 7NS | — |
| 5TYN | alpha-esterase-7 in complex with [3-bromo-5-(pyrrolidin-1-yl)phenyl]borinic acid | x-ray diffraction | A | 7NS | 3 (best 0.77) |
| 5TYN | Alpha-esterase-7 in complex with [3-bromo-5-(pyrrolidin-1-yl) PHENYL]BORINIC acid | x-ray diffraction | A | 7NS | — |
| 5TYO | alpha-esterase-7 in complex with [3-(benzyloxy)-4-methylphenyl]borinic acid | x-ray diffraction | A | 7NM | — |
| 5TYO | Alpha-esterase-7 in complex with [3-(benzyloxy)-4-METHYLPHENYL]BORINIC acid | x-ray diffraction | A | 7NM | — |
| 5TYP | Alpha-esterase-7 in complex with (3-bromo-4-METHYLPHENYL)BORONIC acid | x-ray diffraction | A | 7NJ | — |
Ligands
- 7NS · [3-bromo-5-(pyrrolidin-1-yl)phenyl]borinic acid · in 3 records
- 7N4 · {3-chloro-4-[(2-fluorophenyl)methoxy]phenyl}borinic acid · in 2 records
- 7N7 · naphthalen-2-ylboronic acid · in 2 records
- 7NM · [3-(benzyloxy)-4-methylphenyl]borinic acid · in 2 records
- DPF · Diethyl hydrogen phosphate · in 2 records
- 7ND · (3-bromo-5-phenoxyphenyl)boronic acid · in 1 record
- 7NJ · (3-bromo-4-methylphenyl)boronic acid · in 1 record
Elsewhere
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