MolNFT v1 · #122638 · protein
The alpha-esterase-7 carboxylesterase, E3, from the blowfly lucilia cuprina: apo-enzyme qfit multi-conformer model
5IVD · Carboxylic ester hydrolase: “The alpha-esterase-7 carboxylesterase, E3, from the blowfly lucilia cuprina: apo-enzyme qfit multi-conformer…”. X-ray diffraction, 4 pockets (best druggability 0.73). MolNFT v1 #122638 on GenesisL1: 3D…
- PDB
- 5IVD
- Type
- protein
- Length
- 566 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carboxylic ester hydrolase
- EC
- 3.1.1.-
- UniProt
- Q25252
- Pockets
- 4 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Carboxylic ester hydrolase (EC 3.1.1.-) | protein | 566 | 37% helix, 16% strand | Q25252 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 579 | 0.73 | 0.80 | 51 | empty |
| 2 | 262 | 0.64 | 0.82 | 36 | empty |
| 3 | 116 | 0.43 | 0.77 | 24 | empty |
| 4 | 77 | 0.36 | 0.76 | 22 | empty |
Compared structures
- 5IVD · The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina: apo-enzyme… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q25252
- Elsewhere: RCSB PDB 5IVD · PDBe 5IVD · UniProt Q25252
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.