UniProt Q15554
Telomeric repeat-binding factor 2 (Q15554)
Telomeric repeat-binding factor 2 (UniProt Q15554): 28 experimental structures and 1 predicted model on GenesisL1, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15554
- Protein
- Telomeric repeat-binding factor 2
- Experimental structures
- 28
- Predicted models
- 1
- Pockets
- 27 · 3 records with a druggable one
Structures
29 records of Q15554 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H6P | Dimeristion domain from human TRF2 | x-ray diffraction | A, B | — | — |
| 1H6P | Dimeristion domain from human TRF2 | x-ray diffraction | A, B | — | — |
| 1VF9 | Solution Structure Of Human Trf2 | solution nmr | A | — | — |
| 1VF9 | Solution structure of human TRF2 | solution nmr | A | — | — |
| 1VFC | Solution Structure Of The DNA Complex Of Human Trf2 | solution nmr | A | — | — |
| 1VFC | Solution structure of the DNA complex of human TRF2 | solution nmr | A | — | — |
| 1W0U | hTRF2 DNA-binding domain in complex with telomeric DNA. | x-ray diffraction | A, B | — | — |
| 1W0U | HTRF2 DNA-binding domain in complex with telomeric DNA. | x-ray diffraction | A, B | — | — |
| 1XG1 | Solution structure of Myb-domain of human TRF2 | solution nmr | A | — | — |
| 1XG1 | Solution structure of myb-domain of human TRF2 | solution nmr | A | — | — |
| 3BU8 | Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex | x-ray diffraction | A, B | — | — |
| 3BU8 | Crystal structure of TRF2 trfh domain and TIN2 peptide complex | x-ray diffraction | A, B | — | — |
| 3BUA | Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex | x-ray diffraction | A, B, C, D | — | — |
| 3BUA | Crystal structure of TRF2 trfh domain and apollo peptide complex | x-ray diffraction | A, B, C, D | — | — |
| 3K6G | Crystal structure of Rap1 and TRF2 complex | x-ray diffraction | D, E, F | — | — |
| 3K6G | Crystal structure of RAP1 and TRF2 complex | x-ray diffraction | D, E, F | — | — |
| 3SJM | Crystal Structure Analysis of TRF2-Dbd-DNA complex | x-ray diffraction | A, B | — | — |
| 3SJM | Crystal structure analysis of TRF2-dbd-DNA complex | x-ray diffraction | A, B | — | — |
| 4M7C | Crystal structure of the TRF2-binding motif of SLX4 in complex with the TRFH domain of TRF2 | x-ray diffraction | A, B | — | — |
| 4M7C | Crystal structure of the TRF2-binding motif of SLX4 in complex with the trfh domain of TRF2 | x-ray diffraction | A, B | — | — |
| 4RQI | Structure of TRF2/RAP1 secondary interaction binding site | x-ray diffraction | A, B, C, D | — | — |
| 4RQI | Structure of TRF2/RAP1 secondary interaction binding site | x-ray diffraction | A, B, C, D | — | — |
| 5WQD | Crystal structure of TRF2 TRFH in complex with an NBS1 peptide | x-ray diffraction | A, B, C, D, E, F, G | — | 20 (best 0.78) |
| 5WQD | Crystal structure of TRF2 trfh in complex with an NBS1 peptide | x-ray diffraction | A, B, C, D, E, F, G | — | — |
| 5XYF | Crystal structure of the human TIN2-TPP1-TRF2 telomeric complex | x-ray diffraction | C | — | — |
| 6J67 | Crystal structure of the compound 34 in a complex with TRF2 | x-ray diffraction | A | — | — |
| 7C5D | Crystal structure of TRF2 TRFH domain in complex with a MCPH1 peptide | x-ray diffraction | A, B | — | 4 (best 0.76) |
| 7C5D | Crystal structure of TRF2 trfh domain in complex with a MCPH1 peptide | x-ray diffraction | A, B | — | — |
| Q15554 | AlphaFold monomer V2.0 prediction for telomeric repeat-binding factor 2 (Q15554) | predicted | A | — | 3 (best 0.51) |
Experiment against prediction
- 3BU8 chain A against the predicted model Q15554: TM-score 0.99, RMSD 0.65 Å
- 3BU8 chain A against the predicted model Q15554: TM-score 0.99, RMSD 0.65 Å
- 4RQI chain B against the predicted model Q15554: TM-score 0.99, RMSD 0.63 Å
- 4RQI chain B against the predicted model Q15554: TM-score 0.99, RMSD 0.63 Å
- 6J67 chain A against the predicted model Q15554: TM-score 0.99, RMSD 0.63 Å
- 5WQD chain D against the predicted model Q15554: TM-score 0.99, RMSD 0.64 Å
- 5WQD chain D against the predicted model Q15554: TM-score 0.99, RMSD 0.64 Å
- 5WQD chain F against the predicted model Q15554: TM-score 0.99, RMSD 0.65 Å
- 5WQD chain F against the predicted model Q15554: TM-score 0.99, RMSD 0.65 Å
- 3BUA chain A against the predicted model Q15554: TM-score 0.98, RMSD 0.72 Å
Elsewhere
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