MolNFT v1 · #461134 · protein
AlphaFold monomer V2.0 prediction for telomeric repeat-binding factor 2 (Q15554)
Q15554: “AlphaFold monomer V2.0 prediction for telomeric repeat-binding factor 2 (Q15554)”. 3 pockets (best druggability 0.51). MolNFT v1 #461134 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q15554
- Type
- protein
- Length
- 542 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4Df2295c22880C2DF36CDC12E29D3D67cE553Ddd
- Molecule
- Telomeric repeat-binding factor 2
- UniProt
- Q15554
- Pockets
- 3 · best druggability 0.51
Structure
1 distinct chain · 41% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Telomeric repeat-binding factor 2 | protein | 542 | 41% helix, 0% strand | Q15554 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 149 | 0.51 | 0.79 | 21 | empty |
| 2 | 123 | 0.43 | 0.77 | 21 | empty |
| 3 | 105 | 0.41 | 0.76 | 13 | empty |
Compared structures
- 3BU8 · Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex · an experimental structure of the same protein · chain A against B, TM-score 0.38
- 3BU8 · Crystal structure of TRF2 trfh domain and TIN2 peptide complex · an experimental structure of the same protein · chain A against B, TM-score 0.38
- 5WQD · Crystal structure of TRF2 trfh in complex with an NBS1 peptide · an experimental structure of the same protein · chain A against C, TM-score 0.37
- 5WQD · Crystal structure of TRF2 TRFH in complex with an NBS1 peptide · an experimental structure of the same protein · chain A against C, TM-score 0.37
- 6J67 · Crystal structure of the compound 34 in a complex with TRF2 · an experimental structure of the same protein · chain A against A, TM-score 0.37
- 6J67 · Crystal structure of the compound 34 in a complex with TRF2 · an experimental structure of the same protein · chain A against A, TM-score 0.37
- 4RQI · Structure of TRF2/RAP1 secondary interaction binding site · an experimental structure of the same protein · chain A against B, TM-score 0.37
- 4RQI · Structure of TRF2/RAP1 secondary interaction binding site · an experimental structure of the same protein · chain A against B, TM-score 0.37
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15554
- Elsewhere: UniProt Q15554 · AlphaFold DB Q15554
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.