UniProt Q15116
Programmed cell death protein 1 (Q15116)
Programmed cell death protein 1 (UniProt Q15116): 48 experimental structures on GenesisL1, 6 ligands bound, 53 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q15116
- Protein
- Programmed cell death protein 1
- Experimental structures
- 48
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 53 · 7 records with a druggable one
Structures
48 records of Q15116 in the MolNFT archive: 48 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2M2D | Human programmed cell death 1 receptor | solution nmr | A | — | — |
| 2M2D | Human programmed cell death 1 receptor | solution nmr | A | — | — |
| 3RRQ | Crystal structure of the extracellular domain of human PD-1 | x-ray diffraction | A | — | — |
| 3RRQ | Crystal structure of the extracellular domain of human pd-1 | x-ray diffraction | A | — | — |
| 4ZQK | Structure of the complex of human programmed death-1 (PD-1) and its ligand PD-L1. | x-ray diffraction | B | — | — |
| 4ZQK | Structure of the complex of human programmed death-1 (pd-1) and its ligand pd-L1. | x-ray diffraction | B | — | — |
| 5B8C | High resolution structure of the human PD-1 in complex with pembrolizumab Fv | x-ray diffraction | C, F, I, L | — | 11 (best 0.74) |
| 5B8C | High resolution structure of the human pd-1 in complex with pembrolizumab fv | x-ray diffraction | C, F, I, L | — | — |
| 5GGR | PD-1 in complex with nivolumab Fab | x-ray diffraction | Y, Z | — | 7 (best 0.55) |
| 5GGR | Pd-1 in complex with nivolumab Fab | x-ray diffraction | Y, Z | — | — |
| 5GGS | PD-1 in complex with pembrolizumab Fab | x-ray diffraction | Y, Z | — | 4 (best 0.46) |
| 5GGS | Pd-1 in complex with pembrolizumab Fab | x-ray diffraction | Y, Z | — | — |
| 5IUS | Crystal structure of human PD-L1 in complex with high affinity PD-1 mutant | x-ray diffraction | A, B | — | — |
| 5IUS | Crystal structure of human pd-L1 in complex with high affinity pd-1 mutant | x-ray diffraction | A, B | — | — |
| 5JXE | Human PD-1 ectodomain complexed with Pembrolizumab Fab | x-ray diffraction | A, B | — | — |
| 5JXE | Human pd-1 ectodomain complexed with pembrolizumab Fab | x-ray diffraction | A, B | — | — |
| 5WT9 | Complex structure of PD-1 and nivolumab-Fab | x-ray diffraction | G | NAG, FUC | — |
| 5WT9 | Complex structure of pd-1 and nivolumab-Fab | x-ray diffraction | G | NAG, FUC | — |
| 6HIG | Hpd-1/NBO1A Fab complex | x-ray diffraction | B | — | — |
| 6J14 | Complex structure of gy-14 and pd-1 | x-ray diffraction | G | — | — |
| 6J15 | Complex structure of GY-5 Fab and PD-1 | x-ray diffraction | C, D | NAG, FUC | — |
| 6J15 | Complex structure of gy-5 Fab and pd-1 | x-ray diffraction | C, D | NAG, FUC | — |
| 6JBT | Complex structure of toripalimab-Fab and PD-1 | x-ray diffraction | F | NAG, FUC | 1 (best 0.40) |
| 6JBT | Complex structure of toripalimab-Fab and pd-1 | x-ray diffraction | F | NAG, FUC | — |
| 6JJP | Crystal structure of Fab of a pd-1 monoclonal antibody MW11-H317 in complex with pd-1 | x-ray diffraction | C, F | NAG, FUC | — |
| 6K0Y | Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor | x-ray diffraction | C | — | 2 (best 0.43) |
| 6K0Y | Study of the interactions of a novel monoclonal antibody, MAB059C, with the hpd-1 receptor | x-ray diffraction | C | — | — |
| 6UMT | High-affinity human pd-1 pd-L2 complex | x-ray diffraction | A | MG | — |
| 6UMU | Human apo pd-1 triple mutant | x-ray diffraction | A | CL | — |
| 6UMV | Human apo PD-1 double mutant | x-ray diffraction | A | CL | — |
| 6UMV | Human apo pd-1 double mutant | x-ray diffraction | A | CL | — |
| 6XKR | Structure of sasanlimab Fab in complex with pd-1 | x-ray diffraction | P | — | — |
| 7BXA | Crystal structure of pd-1 in complex with tislelizumab Fab | x-ray diffraction | A, P | — | — |
| 7CGW | Complex structure of PD-1 and tislelizumab Fab | x-ray diffraction | C, P | NAG | 5 (best 0.54) |
| 7CGW | Complex structure of pd-1 and tislelizumab Fab | — | — | — | |
| 7CU5 | N-glycosylation of pd-1 and glycosylation dependent binding of pd-1 specific monoclonal antibody… | x-ray diffraction | E, Q | NAG, MAN, FUC | — |
| 7E9B | Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical… | x-ray diffraction | C | — | — |
| 7E9B | Structural basis of HLX10 pd-1 receptor recognition, a promising anti- pd-1 antibody clinical… | x-ray diffraction | C | — | — |
| 7VUX | Complex structure of PD1 and 609A-Fab | x-ray diffraction | A | THR, MG | 4 (best 0.52) |
| 7VUX | Complex structure of PD1 and 609A-Fab | x-ray diffraction | A | MG | — |
| 7WSL | PD-1 in complex with Dostarlimab | x-ray diffraction | D | — | 2 (best 0.43) |
| 7WSL | Pd-1 in complex with dostarlimab | x-ray diffraction | D | — | — |
| 7WVM | The complex structure of PD-1 and cemiplimab | x-ray diffraction | E, F | — | 5 (best 0.71) |
| 7WVM | The complex structure of pd-1 and cemiplimab | x-ray diffraction | E, F | — | — |
| 8EQ6 | PD1 signaling receptor bound to FAB Complex | x-ray diffraction | A | — | 2 (best 0.55) |
| 8GY5 | High-resolution structure of the cemiplimab Fab in complex with PD-1 | x-ray diffraction | Q, P | — | 8 (best 0.57) |
| 8U32 | Crystal structure of PD-1 in complex with a Fab | x-ray diffraction | A, D | NAG | 2 (best 0.41) |
| Q15116 | AlphaFold monomer V2.0 prediction for programmed cell death protein 1 (Q15116) | — | — | — |
Ligands
Elsewhere
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