UniProt Q15029
116 kDa U5 small nuclear ribonucleoprotein component (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (UniProt Q15029): 39 experimental structures on GenesisL1, 2 ligands bound, 63 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q15029
- Protein
- 116 kDa U5 small nuclear ribonucleoprotein component
- Experimental structures
- 39
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 63 · 17 records with a druggable one
Structures
39 records of Q15029 in the MolNFT archive: 39 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCR | 3D structure determination of the human*U4/U6.U5* tri-snRNP complex | electron microscopy | B | — | — |
| 3JCR | 3D structure determination of the HUMAN*U4/U6.U5* tri-snrnp complex | electron microscopy | B | — | — |
| 5MQF | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | electron microscopy | B | — | — |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | B | — | 5 (best 0.87) |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | B | — | — |
| 5XJC | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | electron microscopy | C | GTP, MG | — |
| 5Z58 | Cryo-EM structure of a human activated spliceosome (early bact) at 4.9 ångström. | electron microscopy | C | GTP, MG | — |
| 6AH0 | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | electron microscopy | C | GTP, MG | — |
| 6AH0 | The cryo-EM structure of the precusor of human pre-catalytic spliceosome (pre-B complex) | electron microscopy | C | GTP, MG | — |
| 6FF4 | human Bact spliceosome core structure | electron microscopy | B | GTP | 2 (best 0.84) |
| 6FF4 | Human bact spliceosome core structure | electron microscopy | B | GTP | — |
| 6FF7 | Human bact spliceosome core structure | electron microscopy | B | GTP | — |
| 6ICZ | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 ångström | electron microscopy | C | GTP, MG | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9… | electron microscopy | C | GTP, MG | — |
| 6ID0 | Cryo-EM structure of a human intron lariat spliceosome prior to PRP43 loaded (ILS1 complex) at 2.9… | electron microscopy | C | GTP, MG | — |
| 6ID1 | Cryo-EM structure of a human intron lariat spliceosome after PRP43 loaded (ILS2 complex) at 2.9… | electron microscopy | C | GTP, MG | — |
| 6QW6 | Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. | electron microscopy | 5C | MG, GTP | 5 (best 0.82) |
| 6QX9 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | electron microscopy | 5C | MG, GTP | 2 (best 0.81) |
| 6ZYM | Human C Complex Spliceosome - High-resolution CORE | electron microscopy | B | GTP | 4 (best 0.85) |
| 6ZYM | Human C complex spliceosome - high-resolution core | electron microscopy | B | GTP | — |
| 7AAV | Human pre-bact-2 spliceosome core structure | electron microscopy | r | GTP, MG | — |
| 7ABI | Human pre-bact-2 spliceosome | electron microscopy | r | GTP, MG | — |
| 7DVQ | Cryo-EM structure of the activated human minor spliceosome (minor bact complex) | electron microscopy | C | GTP, MG | — |
| 7W59 | The cryo-EM structure of human pre-C*-I complex | electron microscopy | C | GTP, MG | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | C | GTP, MG | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | C | GTP, MG | — |
| 8C6J | Human spliceosomal PM5 C* complex | electron microscopy | C | MG, GTP | 2 (best 0.83) |
| 8H6E | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | electron microscopy | 5C | MG, GTP | 4 (best 0.83) |
| 8I0U | The cryo-EM structure of human Bact-IV complex | electron microscopy | C | GTP, MG | 3 (best 0.88) |
| 8Q7N | cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) | electron microscopy | C | — | 1 (best 0.82) |
| 8Q7V | Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1) | electron microscopy | C | MG, GTP | 4 (best 0.82) |
| 8Q7X | Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4) | electron microscopy | C | MG, GTP | 4 (best 0.81) |
| 8Q91 | Structure of the human 20S U5 snRNP core | electron microscopy | C | GTP | 7 (best 0.81) |
| 8QPE | Cryo-EM Structure of Pre-B-like Complex (core part) | electron microscopy | C | — | 2 (best 0.83) |
| 8QPK | Cryo-EM Structure of Pre-B+5'ss Complex (core part) | electron microscopy | C | — | 8 (best 0.89) |
| 8R09 | Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex | electron microscopy | C | — | 3 (best 0.83) |
| 8R0B | Cryo-EM structure of the cross-exon pre-B+ATP complex | electron microscopy | C | — | 4 (best 0.84) |
| 8Y6O | Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP… | electron microscopy | D | GTP, MG | 3 (best 0.83) |
| Q15029 | AlphaFold monomer V2.0 prediction for 116 kda U5 small nuclear ribonucleoprotein component (Q15029) | — | — | — |
Ligands
Elsewhere
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