UniProt Q14676
Mediator of DNA damage checkpoint protein 1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (UniProt Q14676): 18 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14676
- Protein
- Mediator of DNA damage checkpoint protein 1
- Experimental structures
- 18
- Predicted models
- 1
Structures
19 records of Q14676 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ADO | Crystal Structure Of The Brct Repeat Region From The Mediator of DNA damage checkpoint protein 1… | x-ray diffraction | A, B | — | — |
| 2ADO | Crystal structure of the brct repeat region from the mediator of DNA damage checkpoint protein 1… | x-ray diffraction | A, B | — | — |
| 2AZM | Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX | x-ray diffraction | A, B | — | — |
| 2AZM | Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX | x-ray diffraction | A, B | — | — |
| 2ETX | Crystal Structure of MDC1 Tandem BRCT Domains | x-ray diffraction | A, B | — | — |
| 2ETX | Crystal structure of MDC1 tandem brct domains | x-ray diffraction | A, B | — | — |
| 3K05 | The crystal structure of MDC1 BRCT T2067D in complex with a minimal recognition tetrapeptide with… | x-ray diffraction | A, B | — | — |
| 3K05 | The crystal structure of MDC1 brct T2067D in complex with a minimal recognition tetrapeptide with… | x-ray diffraction | A, B | — | — |
| 3UMZ | Crystal Structure of the human MDC1 FHA Domain | x-ray diffraction | A, B | — | — |
| 3UMZ | Crystal structure of the human MDC1 fha domain | x-ray diffraction | A, B | — | — |
| 3UN0 | Crystal Structure of MDC1 FHA Domain | x-ray diffraction | B, A | — | — |
| 3UN0 | Crystal structure of MDC1 fha domain | x-ray diffraction | B, A | — | — |
| 3UNM | Crystal Structure of The Human MDC1 FHA Domain | x-ray diffraction | A, B | — | — |
| 3UNM | Crystal structure of the human MDC1 fha domain | x-ray diffraction | A, B | — | — |
| 3UNN | Monomeric structure of the human MDC1 FHA domain in complex with an MDC1 phospho-T4 peptide | x-ray diffraction | A, B | — | — |
| 3UNN | Monomeric structure of the human MDC1 fha domain in complex with an MDC1 phospho-T4 peptide | x-ray diffraction | A, B | — | — |
| 3UOT | Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1… | x-ray diffraction | A, B, D, E | — | — |
| 3UOT | Crystal structure of MDC1 fha domain in complex with a phosphorylated peptide from the MDC1… | x-ray diffraction | A, B, D, E | — | — |
| Q14676 | AlphaFold monomer V2.0 prediction for mediator of DNA damage checkpoint protein 1 (Q14676) | predicted | A | — | — |
Experiment against prediction
- 3K05 chain A against the predicted model Q14676: TM-score 0.99, RMSD 0.60 Å
- 3K05 chain A against the predicted model Q14676: TM-score 0.99, RMSD 0.60 Å
- 2AZM chain A against the predicted model Q14676: TM-score 0.98, RMSD 0.68 Å
- 2AZM chain A against the predicted model Q14676: TM-score 0.98, RMSD 0.68 Å
- 2AZM chain B against the predicted model Q14676: TM-score 0.98, RMSD 0.87 Å
- 2AZM chain B against the predicted model Q14676: TM-score 0.98, RMSD 0.87 Å
- 3UOT chain B against the predicted model Q14676: TM-score 0.98, RMSD 0.67 Å
- 3UOT chain B against the predicted model Q14676: TM-score 0.98, RMSD 0.67 Å
- 3UMZ chain A against the predicted model Q14676: TM-score 0.97, RMSD 0.76 Å
- 3UMZ chain A against the predicted model Q14676: TM-score 0.97, RMSD 0.76 Å
Elsewhere
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