UniProt Q14498
RNA-binding protein 39 (Q14498)
RNA-binding protein 39 (UniProt Q14498): 17 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14498
- Protein
- RNA-binding protein 39
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 6 · 1 record with a druggable one
Structures
18 records of Q14498 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JRS | Solution NMR Structure of CAPER RRM2 Domain. Northeast Structural Genomics Target HR4730A | solution nmr | A | — | — |
| 2JRS | Solution NMR structure of caper RRM2 domain. northeast structural genomics target HR4730A | solution nmr | A | — | — |
| 2MHN | NMR structure of the first RRM domain of the protein RBM39 from Homo sapiens | solution nmr | A | — | — |
| 2MHN | NMR structure of the first rrm domain of the protein RBM39 from homo sapiens | solution nmr | A | — | — |
| 4OO6 | Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) | x-ray diffraction | B | — | — |
| 4OO6 | Crystal structure of human kap-BETA2 bound to the nls of HCC1 (hepato cellular carcinoma protein 1) | x-ray diffraction | B | — | — |
| 4OZ0 | Crystal structure of human CAPERalpha U2AF homology motif (apo-state) | x-ray diffraction | A, B | — | — |
| 4OZ0 | Crystal structure of human caperalpha U2AF homology motif (apo-state) | x-ray diffraction | A, B | — | — |
| 4OZ1 | Crystal structure of human CAPERalpha UHM bound to SF3b155 ULM5 | x-ray diffraction | A, B | — | — |
| 4OZ1 | Crystal structure of human caperalpha uhm bound to SF3B155 ULM5 | x-ray diffraction | A, B | — | — |
| 4YUD | Crystal structure of a RNA binding motif protein 39 (RBM39) from Homo sapiens at 1.28 A resolution | x-ray diffraction | A | — | — |
| 4YUD | Crystal structure of a RNA binding motif protein 39 (RBM39) from homo sapiens at 1.28 a resolution | x-ray diffraction | A | — | — |
| 6Q0R | Structure of DDB1-DDA1-DCAF15 complex bound to E7820 and RBM39 | x-ray diffraction | D | O6M | — |
| 6Q0V | Structure of DDB1-DDA1-DCAF15 complex bound to tasisulam and RBM39 | x-ray diffraction | D | P7M | — |
| 6Q0W | Structure of DDB1-DDA1-DCAF15 complex bound to Indisulam and RBM39 | x-ray diffraction | D | EF6 | 3 (best 0.85) |
| 6Q0W | Structure of DDB1-DDA1-DCAF15 complex bound to indisulam and RBM39 | x-ray diffraction | D | EF6 | — |
| 7Q33 | Solution structure of RBM39 RRM2 bound to 5'-AGCUUUG-3 | solution nmr | A | — | — |
| Q14498 | AlphaFold monomer V2.0 prediction for RNA-binding protein 39 (Q14498) | predicted | A | — | 3 (best 0.42) |
Ligands
Experiment against prediction
- 4OZ0 chain B against the predicted model Q14498: TM-score 0.96, RMSD 0.83 Å
- 4OZ0 chain B against the predicted model Q14498: TM-score 0.96, RMSD 0.83 Å
- 4OZ1 chain B against the predicted model Q14498: TM-score 0.96, RMSD 0.88 Å
- 4OZ1 chain B against the predicted model Q14498: TM-score 0.96, RMSD 0.88 Å
- 6Q0V chain D against the predicted model Q14498: TM-score 0.96, RMSD 0.66 Å
- 6Q0W chain D against the predicted model Q14498: TM-score 0.95, RMSD 0.71 Å
- 6Q0W chain D against the predicted model Q14498: TM-score 0.95, RMSD 0.71 Å
- 6Q0R chain D against the predicted model Q14498: TM-score 0.95, RMSD 0.78 Å
- 4OZ0 chain A against the predicted model Q14498: TM-score 0.93, RMSD 1.27 Å
- 4OZ0 chain A against the predicted model Q14498: TM-score 0.93, RMSD 1.27 Å
Elsewhere
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