UniProt Q13263
Transcription intermediary factor 1-beta (Q13263)
Transcription intermediary factor 1-beta (UniProt Q13263), EC 2.3.2.27, 3.2.1.17: 15 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 68 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q13263
- Protein
- Transcription intermediary factor 1-beta
- EC
- 2.3.2.27, 3.2.1.17
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 68 · 5 records with a druggable one
Structures
16 records of Q13263 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FP0 | Solution structure of the phd domain from the kap-1 corepressor | solution nmr | A | ZN | — |
| 1FP0 | Solution structure of the phd domain from the kap-1 corepressor | solution nmr | A | ZN | — |
| 2RO1 | NMR Solution Structures of Human KAP1 PHD finger-bromodomain | solution nmr | A | ZN | 2 (best 0.36) |
| 2RO1 | NMR solution structures of human KAP1 phd finger-bromodomain | solution nmr | A | ZN | 2 (best 0.36) |
| 2YVR | Crystal structure of MS1043 | x-ray diffraction | A, B | ZN | 3 (best 0.41) |
| 2YVR | Crystal structure of MS1043 | x-ray diffraction | A, B | ZN | 3 (best 0.41) |
| 6H3A | Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain. | x-ray diffraction | A, F | ZN | 9 (best 0.80) |
| 6H3A | Crystal structure of the KAP1 rbcc domain in complex with the SMARCAD1 CUE1 domain. | x-ray diffraction | A, F | ZN | 9 (best 0.80) |
| 6I9H | Solution structure of TRIM28 RING domain | solution nmr | A | ZN | — |
| 6I9H | Solution structure of TRIM28 ring domain | solution nmr | A | ZN | — |
| 6QAJ | Structure of the tripartite motif of KAP1/TRIM28 | x-ray diffraction | A, B | ZN | 14 (best 0.75) |
| 6QAJ | Structure of the tripartite motif of KAP1/TRIM28 | x-ray diffraction | A, B | ZN | 14 (best 0.75) |
| 6QU1 | Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain at 3.7 angstrom… | x-ray diffraction | A | ZN | — |
| 6QU1 | Crystal structure of the KAP1 rbcc domain in complex with the SMARCAD1 CUE1 domain at 3.7 ångström… | x-ray diffraction | A | ZN | — |
| 7Z36 | Crystal structure of the KAP1 tripartite motif in complex with the ZNF93 KRAB domain | x-ray diffraction | A, B | ZN | 8 (best 0.80) |
| Q13263 | AlphaFold monomer V2.0 prediction for transcription intermediary factor 1-beta (Q13263) | predicted | A | — | 4 (best 0.39) |
Ligands
- ZN · Zinc ion · in 15 records
Experiment against prediction
- 6QU1 chain A against the predicted model Q13263: TM-score 0.89, RMSD 2.00 Å
- 6QU1 chain A against the predicted model Q13263: TM-score 0.89, RMSD 2.00 Å
- 2YVR chain A against the predicted model Q13263: TM-score 0.89, RMSD 1.11 Å
- 2YVR chain A against the predicted model Q13263: TM-score 0.89, RMSD 1.11 Å
- 6H3A chain F against the predicted model Q13263: TM-score 0.81, RMSD 2.94 Å
- 6H3A chain F against the predicted model Q13263: TM-score 0.81, RMSD 2.94 Å
- 6H3A chain A against the predicted model Q13263: TM-score 0.72, RMSD 3.82 Å
- 6H3A chain A against the predicted model Q13263: TM-score 0.72, RMSD 3.82 Å
- 2RO1 chain A against the predicted model Q13263: TM-score 0.67, RMSD 3.14 Å
- 2RO1 chain A against the predicted model Q13263: TM-score 0.67, RMSD 3.14 Å
Elsewhere
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