UniProt Q12918
Killer cell lectin-like receptor subfamily B member 1 (Q12918)
Killer cell lectin-like receptor subfamily B member 1 (UniProt Q12918): 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q12918
- Protein
- Killer cell lectin-like receptor subfamily B member 1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 17 · 3 records with a druggable one
Structures
7 records of Q12918 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MGR | Human receptor NKR-P1 in glycosylated form, extracellular domain | x-ray diffraction | A, B | NAG, BMA, MAN | 2 (best 0.56) |
| 5MGR | Human receptor nkr-P1 in glycosylated form, extracellular domain | x-ray diffraction | A, B | NAG, MAN, BMA | — |
| 5MGS | Human receptor NKR-P1 in deglycosylated form, extracellular domain | x-ray diffraction | A, B, C, D, E, F, G, H | NAG | 10 (best 0.74) |
| 5MGS | Human receptor nkr-P1 in deglycosylated form, extracellular domain | x-ray diffraction | A, B, C, D, E, F, G, H | NAG | — |
| 5MGT | Complex of human NKR-P1 and LLT1 in deglycosylated forms | x-ray diffraction | C, D, E, F | NAG, SO4, CL | 5 (best 0.73) |
| 5MGT | Complex of human nkr-P1 and LLT1 in deglycosylated forms | x-ray diffraction | C, D, E, F | NAG, SO4, CL | — |
| Q12918 | AlphaFold monomer V2.0 prediction for killer cell lectin-like receptor subfamily B member 1 (Q12918) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5MGT chain F against the predicted model Q12918: TM-score 0.99, RMSD 0.77 Å
- 5MGS chain F against the predicted model Q12918: TM-score 0.99, RMSD 0.78 Å
- 5MGT chain D against the predicted model Q12918: TM-score 0.98, RMSD 0.80 Å
- 5MGT chain D against the predicted model Q12918: TM-score 0.98, RMSD 0.80 Å
- 5MGS chain C against the predicted model Q12918: TM-score 0.98, RMSD 1.02 Å
- 5MGS chain C against the predicted model Q12918: TM-score 0.98, RMSD 1.02 Å
- 5MGS chain G against the predicted model Q12918: TM-score 0.98, RMSD 0.87 Å
- 5MGS chain A against the predicted model Q12918: TM-score 0.98, RMSD 1.06 Å
- 5MGS chain A against the predicted model Q12918: TM-score 0.98, RMSD 1.06 Å
- 5MGS chain D against the predicted model Q12918: TM-score 0.98, RMSD 1.29 Å
Elsewhere
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