UniProt Q10714
Angiotensin-converting enzyme (Q10714)
Angiotensin-converting enzyme (UniProt Q10714), EC 3.4.15.1: 44 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q10714
- Protein
- Angiotensin-converting enzyme
- EC
- 3.4.15.1
- Experimental structures
- 44
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 1 record with a druggable one
Structures
45 records of Q10714 in the MolNFT archive: 44 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1J36 | Crystal Structure of Drosophila AnCE | x-ray diffraction | A, B | — | — |
| 1J36 | Crystal structure of drosophila ance | x-ray diffraction | A, B | — | — |
| 1J37 | Crystal Structure of Drosophila AnCE | x-ray diffraction | A, B | — | — |
| 1J37 | Crystal structure of drosophila ance | x-ray diffraction | A, B | — | — |
| 1J38 | Crystal Structure of Drosophila AnCE | x-ray diffraction | A, B | — | — |
| 1J38 | Crystal structure of drosophila ance | x-ray diffraction | A, B | — | — |
| 2X8Y | Crystal structure of AnCE | x-ray diffraction | A | — | — |
| 2X8Y | Crystal structure of ance | x-ray diffraction | A | — | — |
| 2X8Z | Crystal structure of AnCE-captopril complex | x-ray diffraction | A | — | — |
| 2X8Z | Crystal structure of ance-captopril complex | x-ray diffraction | A | — | — |
| 2X90 | Crystal structure of AnCE-enalaprilat complex | x-ray diffraction | A | — | — |
| 2X90 | Crystal structure of ance-enalaprilat complex | x-ray diffraction | A | — | — |
| 2X91 | Crystal structure of AnCE-lisinopril complex | x-ray diffraction | A | — | — |
| 2X91 | Crystal structure of ance-lisinopril complex | x-ray diffraction | A | — | — |
| 2X92 | Crystal structure of AnCE-ramiprilat complex | x-ray diffraction | A | — | — |
| 2X92 | Crystal structure of ance-ramiprilat complex | x-ray diffraction | A | — | — |
| 2X93 | Crystal structure of AnCE-trandolaprilat complex | x-ray diffraction | A | — | — |
| 2X93 | Crystal structure of ance-trandolaprilat complex | x-ray diffraction | A | — | — |
| 2X94 | Crystal structure of AnCE-perindoprilat complex | x-ray diffraction | A | — | — |
| 2X94 | Crystal structure of ance-perindoprilat complex | x-ray diffraction | A | — | — |
| 2X95 | Crystal structure of AnCE-lisinopril-tryptophan analogue, lisW-S complex | x-ray diffraction | A | — | — |
| 2X95 | Crystal structure of ance-lisinopril-tryptophan analogue, lisw-S complex | x-ray diffraction | A | — | — |
| 2X96 | Crystal structure of AnCE-RXPA380 complex | x-ray diffraction | A | — | — |
| 2X96 | Crystal structure of ance-RXPA380 complex | x-ray diffraction | A | — | — |
| 2X97 | Crystal structure of AnCE-RXP407 complex | x-ray diffraction | A | — | — |
| 2X97 | Crystal structure of ance-RXP407 complex | x-ray diffraction | A | — | — |
| 2XHM | Crystal structure of AnCE-K26 complex | x-ray diffraction | A | — | — |
| 2XHM | Crystal structure of ance-K26 complex | x-ray diffraction | A | — | — |
| 3ZQZ | Crystal structure of ance in complex with a selenium analogue of captopril | x-ray diffraction | A | — | — |
| 3ZQZ | Crystal structure of ance in complex with a selenium analogue of captopril | x-ray diffraction | A | — | — |
| 4AA1 | Crystal structure of ANCE in complex with Angiotensin-II | x-ray diffraction | A | — | — |
| 4AA1 | Crystal structure of ance in complex with angiotensin-II | x-ray diffraction | A | — | — |
| 4AA2 | Crystal structure of ANCE in complex with bradykinin potentiating peptide b | x-ray diffraction | A | — | — |
| 4AA2 | Crystal structure of ance in complex with bradykinin potentiating peptide B | x-ray diffraction | A | — | — |
| 4ASQ | Crystal structure of ANCE in complex with Bradykinin | x-ray diffraction | A | — | — |
| 4ASQ | Crystal structure of ance in complex with bradykinin | x-ray diffraction | A | — | — |
| 4ASR | Crystal structure of ANCE in complex with Thr6-Bradykinin | x-ray diffraction | A | — | — |
| 4ASR | Crystal structure of ance in complex with THR6-bradykinin | x-ray diffraction | A | — | — |
| 4CA7 | Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FI | x-ray diffraction | A | — | — |
| 4CA7 | Drosophila angiotensin converting enzyme (ance) in complex with a phosphinic tripeptide fi | x-ray diffraction | A | — | — |
| 4CA8 | Drosophila Angiotensin converting enzyme (AnCE) in complex with a phosphinic tripeptide FII | x-ray diffraction | A | — | — |
| 4CA8 | Drosophila angiotensin converting enzyme (ance) in complex with a phosphinic tripeptide fii | x-ray diffraction | A | — | — |
| 5A2R | A New Crystal Structure of the Drosophila melanogaster Angiotensin Converting Enzyme Homologue AnCE. | x-ray diffraction | A | MLT, ZN, NAG | 3 (best 0.86) |
| 5A2R | A new crystal structure of the drosophila melanogaster angiotensin converting enzyme homologue ance. | x-ray diffraction | A | — | — |
| Q10714 | AlphaFold monomer V2.0 prediction for angiotensin-converting enzyme (Q10714) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5A2R chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.67 Å
- 5A2R chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.67 Å
- 2X96 chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.71 Å
- 2X96 chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.71 Å
- 2X8Z chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.71 Å
- 2X8Z chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.71 Å
- 4ASR chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.72 Å
- 4ASR chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.72 Å
- 2X91 chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.71 Å
- 2X91 chain A against the predicted model Q10714: TM-score 0.99, RMSD 0.71 Å
Elsewhere
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