UniProt Q08AG7
Mitotic-spindle organizing protein 1 (Q08AG7)
Mitotic-spindle organizing protein 1 (UniProt Q08AG7): 28 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q08AG7
- Protein
- Mitotic-spindle organizing protein 1
- Experimental structures
- 28
- Predicted models
- 1
- Pockets
- 6 · 5 records with a druggable one
Structures
29 records of Q08AG7 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6L81 | Crystal structure of Homo sapiens GCP5 N-terminus and Mozart1 | x-ray diffraction | B, D | — | — |
| 6L81 | Crystal structure of homo sapiens GCP5 N-terminus and MOZART1 | x-ray diffraction | B, D | — | — |
| 6M33 | Crystal structure of Homo Sapian GCP6 N-terminus and Mozart1 | x-ray diffraction | B | — | 1 (best 0.50) |
| 6M33 | Crystal structure of homo sapian GCP6 N-terminus and MOZART1 | x-ray diffraction | B | — | — |
| 6X0U | Structure of MZT1/GCP3-NHD and MZT1/GCP6-NHD in the gamma-TuRC lumenal bridge | electron microscopy | A, C | — | — |
| 6X0U | Structure of MZT1/GCP3-nhd and MZT1/GCP6-nhd in the gamma-turc lumenal bridge | electron microscopy | A, C | — | — |
| 7QJ0 | Structure of recombinant human gamma-Tubulin Ring Complex 6-spoked assembly intermediate (spokes… | electron microscopy | m, b | — | — |
| 7QJ0 | Structure of recombinant human gamma-tubulin ring complex 6-spoked assembly intermediate (spokes… | electron microscopy | m, b | — | — |
| 7QJ1 | Structure of the recombinant human gamma-Tubulin Ring Complex 6-spoked assembly intermediate… | electron microscopy | m, b | — | — |
| 7QJ1 | Structure of the recombinant human gamma-tubulin ring complex 6-spoked assembly intermediate… | electron microscopy | m, b | — | — |
| 7QJ2 | Structure of recombinant human gamma-Tubulin Ring Complex 8-spoked assembly intermediate (spokes… | electron microscopy | m, k, b | — | 1 (best 0.82) |
| 7QJ2 | Structure of recombinant human gamma-tubulin ring complex 8-spoked assembly intermediate (spokes… | electron microscopy | m, k, b | — | — |
| 7QJ3 | Structure of recombinant human gamma-Tubulin Ring Complex 8-spoked assembly intermediate (spokes… | electron microscopy | o, m, b | — | 1 (best 0.80) |
| 7QJ3 | Structure of recombinant human gamma-tubulin ring complex 8-spoked assembly intermediate (spokes… | electron microscopy | o, m, b | — | — |
| 7QJ4 | Structure of recombinant human gamma-Tubulin Ring Complex 10-spoked assembly intermediate (spokes… | electron microscopy | o, m, k, b | — | — |
| 7QJ4 | Structure of recombinant human gamma-tubulin ring complex 10-spoked assembly intermediate (spokes… | electron microscopy | o, m, k, b | — | — |
| 7QJ5 | Structure of recombinant human gamma-Tubulin Ring Complex (spokes 1-14) | electron microscopy | b, g, i, m, k, d | — | 1 (best 0.79) |
| 7QJ6 | Structure of recombinant human gamma-tubulin ring complex 10-spoked assembly intermediate (spokes… | electron microscopy | b, k, m, i, d | — | — |
| 7QJ7 | Structure of recombinant human gamma-Tubulin Ring Complex 12-spoked assembly intermediate (spokes… | electron microscopy | b, g, i, k, m, d | — | — |
| 7QJ9 | Structure of recombinant human gamma-Tubulin Ring Complex 10-spoked assembly intermediate (spokes… | electron microscopy | b, i, m, k, d | — | — |
| 7QJ9 | Structure of recombinant human gamma-tubulin ring complex 10-spoked assembly intermediate (spokes… | electron microscopy | b, i, m, k, d | — | — |
| 7QJA | Structure of recombinant human gamma-Tubulin Ring Complex 12-spoked assembly intermediate (spokes… | electron microscopy | b, g, i, k, m, d | — | — |
| 7QJB | Structure of recombinant human gamma-Tubulin Ring Complex 12-spoked assembly intermediate (spokes… | electron microscopy | i, k, m, b, d | — | — |
| 7QJC | Structure of recombinant human gamma-Tubulin Ring Complex (spokes 1-14, homogeneous dataset) | electron microscopy | b, g, i, k, m, d | — | — |
| 7QJD | Structure of recombinant human gamma-Tubulin Ring Complex without actin | electron microscopy | o, k, i, g, m, b, d | — | — |
| 8RX1 | CryoEM structure of the gTuRC-CM1dim complex | electron microscopy | a, c | — | 1 (best 0.75) |
| 8VRJ | Rigid body fitted model for gamma tubulin ring complex capped microtubule | electron microscopy | 7, 8 | — | — |
| 8VRK | Rigid body fitted model for refined density map of gamma tubulin ring complex capped microtubule | electron microscopy | 7, 8 | — | — |
| Q08AG7 | AlphaFold monomer V2.0 prediction for mitotic-spindle organizing protein 1 (Q08AG7) | predicted | A | — | 1 (best 0.30) |
Experiment against prediction
- 6L81 chain B against the predicted model Q08AG7: TM-score 0.97, RMSD 0.48 Å
- 6L81 chain B against the predicted model Q08AG7: TM-score 0.97, RMSD 0.48 Å
- 6L81 chain D against the predicted model Q08AG7: TM-score 0.97, RMSD 0.44 Å
- 6L81 chain D against the predicted model Q08AG7: TM-score 0.97, RMSD 0.44 Å
- 7QJ2 chain b against the predicted model Q08AG7: TM-score 0.94, RMSD 0.71 Å
- 7QJ2 chain m against the predicted model Q08AG7: TM-score 0.94, RMSD 0.71 Å
- 7QJ2 chain m against the predicted model Q08AG7: TM-score 0.94, RMSD 0.71 Å
- 7QJ2 chain k against the predicted model Q08AG7: TM-score 0.94, RMSD 0.71 Å
- 7QJC chain b against the predicted model Q08AG7: TM-score 0.94, RMSD 0.71 Å
- 6X0U chain A against the predicted model Q08AG7: TM-score 0.94, RMSD 0.73 Å
Elsewhere
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