UniProt Q07478
ATP-dependent RNA helicase SUB2 (Q07478)
ATP-dependent RNA helicase SUB2 (UniProt Q07478), EC 3.6.4.13: 9 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q07478
- Protein
- ATP-dependent RNA helicase SUB2
- EC
- 3.6.4.13
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 31 · 5 records with a druggable one
Structures
10 records of Q07478 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5SUP | Crystal structure of the Sub2-Yra1 complex in association with RNA | x-ray diffraction | A, B, C | ADP, BEF, MG | 15 (best 0.85) |
| 5SUP | Crystal structure of the SUB2-YRA1 complex in association with RNA | x-ray diffraction | A, B, C | ADP, BEF, MG | — |
| 5SUQ | Crystal structure of the tho-SUB2 complex | x-ray diffraction | A, C | KEG | — |
| 7APX | yeast THO-Sub2 complex | electron microscopy | F | — | 5 (best 0.81) |
| 7APX | Yeast tho-SUB2 complex | electron microscopy | F | — | — |
| 7LUV | Cryo-EM structure of the yeast THO-Sub2 complex | electron microscopy | M | — | 4 (best 0.71) |
| 7LUV | Cryo-EM structure of the yeast tho-SUB2 complex | electron microscopy | M | — | — |
| 7V2Y | cryo-EM structure of yeast THO complex with Sub2 | electron microscopy | F | — | 3 (best 0.85) |
| 7V2Y | Cryo-EM structure of yeast tho complex with SUB2 | electron microscopy | F | — | — |
| Q07478 | AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase SUB2 (Q07478) | predicted | A | — | 4 (best 0.62) |
Ligands
Experiment against prediction
- 5SUP chain C against the predicted model Q07478: TM-score 0.99, RMSD 0.54 Å
- 5SUP chain C against the predicted model Q07478: TM-score 0.99, RMSD 0.54 Å
- 5SUP chain A against the predicted model Q07478: TM-score 0.99, RMSD 0.66 Å
- 5SUP chain A against the predicted model Q07478: TM-score 0.99, RMSD 0.66 Å
- 5SUQ chain A against the predicted model Q07478: TM-score 0.80, RMSD 3.50 Å
- 7APX chain F against the predicted model Q07478: TM-score 0.68, RMSD 4.46 Å
- 7APX chain F against the predicted model Q07478: TM-score 0.68, RMSD 4.46 Å
- 7V2Y chain F against the predicted model Q07478: TM-score 0.67, RMSD 4.40 Å
- 7V2Y chain F against the predicted model Q07478: TM-score 0.67, RMSD 4.40 Å
- 7LUV chain M against the predicted model Q07478: TM-score 0.65, RMSD 4.48 Å
Elsewhere
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