UniProt Q06455
Protein CBFA2T1 (Q06455)
Protein CBFA2T1 (UniProt Q06455): 16 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q06455
- Protein
- Protein CBFA2T1
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
17 records of Q06455 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WQ6 | The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for… | x-ray diffraction | A, B | — | — |
| 1WQ6 | The tetramer structure of the nervy homolgy two (NHR2) domain of AML1- eto is critical for… | x-ray diffraction | A, B | — | — |
| 2DJ8 | Solution Structure of zf-MYND Domain of Protein CBFA2TI (Protein MTG8) | solution nmr | A | — | — |
| 2DJ8 | Solution structure of zf-mynd domain of protein CBFA2TI (protein MTG8) | solution nmr | A | — | — |
| 2KNH | The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide | solution nmr | A | — | — |
| 2KNH | The solution structure of the etafh domain of AML1-eto complexed with heb peptide | solution nmr | A | — | — |
| 2KYG | Structure of the AML1-ETO Nervy Domain - PKA(RIIa) complex and its contribution to AML1-ETO activity | solution nmr | C | — | — |
| 2KYG | Structure of the AML1-eto nervy domain - PKA(RIIA) complex and its contribution to AML1-eto activity | solution nmr | C | — | — |
| 2OD1 | Solution structure of the MYND domain from human AML1-ETO | solution nmr | A | — | — |
| 2OD1 | Solution structure of the mynd domain from human AML1-eto | solution nmr | A | — | — |
| 2ODD | Solution structure of the MYND domain from AML1-ETO complexed with SMRT, a corepressor | solution nmr | A | — | — |
| 2ODD | Solution structure of the mynd domain from AML1-eto complexed with smrt, a corepressor | solution nmr | A | — | — |
| 2PP4 | Solution Structure of ETO-TAFH refined in explicit solvent | solution nmr | A | — | — |
| 2PP4 | Solution structure of eto-tafh refined in explicit solvent | solution nmr | A | — | — |
| 4JOL | Complex structure of AML1-ETO NHR2 domain with HEB fragment | x-ray diffraction | A, B, C, D | — | — |
| 4JOL | Complex structure of AML1-eto NHR2 domain with heb fragment | x-ray diffraction | A, B, C, D | — | — |
| Q06455 | AlphaFold monomer V2.0 prediction for protein CBFA2T1 (Q06455) | predicted | A | — | 2 (best 0.43) |
Experiment against prediction
- 4JOL chain A against the predicted model Q06455: TM-score 0.83, RMSD 1.51 Å
- 4JOL chain A against the predicted model Q06455: TM-score 0.83, RMSD 1.51 Å
- 1WQ6 chain A against the predicted model Q06455: TM-score 0.83, RMSD 1.27 Å
- 1WQ6 chain A against the predicted model Q06455: TM-score 0.83, RMSD 1.27 Å
- 2OD1 chain A against the predicted model Q06455: TM-score 0.74, RMSD 1.74 Å
- 2OD1 chain A against the predicted model Q06455: TM-score 0.74, RMSD 1.74 Å
- 2ODD chain A against the predicted model Q06455: TM-score 0.74, RMSD 1.83 Å
- 2ODD chain A against the predicted model Q06455: TM-score 0.74, RMSD 1.83 Å
- 2KNH chain A against the predicted model Q06455: TM-score 0.69, RMSD 2.66 Å
- 2KNH chain A against the predicted model Q06455: TM-score 0.69, RMSD 2.66 Å
Elsewhere
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