MolNFT v1 · #48306 · protein

Solution structure of eto-tafh refined in explicit solvent

2PP4 · Protein eto: “Solution structure of eto-tafh refined in explicit solvent”. Solution nmr, 2 pockets (best druggability 0.69). MolNFT v1 #48306 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2PP4
Type: protein
Length: 107 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein eto
UniProt: Q06455
Pockets: 2 · best druggability 0.69

Structure

solution nmr · 1 distinct chain · 75% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein eto	protein	107	75% helix, 0% strand	Q06455

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	199	0.69	0.86	31	empty
2	82	0.46	0.80	14	empty

Compared structures

2PP4 · Solution Structure of ETO-TAFH refined in explicit solvent · the same entry in another collection · chain A against A, TM-score 1.00
Q06455 · AlphaFold monomer V2.0 prediction for protein CBFA2T1 (Q06455) · a predicted model of the same protein · chain A against A, TM-score 0.64

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q06455
Elsewhere: RCSB PDB 2PP4 · PDBe 2PP4 · UniProt Q06455

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