MolNFT v1 · #26473 · protein
The tetramer structure of the nervy homolgy two (NHR2) domain of AML1- eto is critical for AML1-ETO'S activity
1WQ6: “The tetramer structure of the nervy homolgy two (NHR2) domain of AML1- eto is critical for AML1-ETO'S activity”. X-ray diffraction. MolNFT v1 #26473 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1WQ6
- Type
- protein
- Length
- 118 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- AML1-eto
- UniProt
- Q06455
Structure
x-ray diffraction · 1 distinct chain · 90% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | AML1-eto | protein | 59 | 90% helix, 0% strand | Q06455 |
Interfaces
1 interface between chains.
- A–B · 1177 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 1WQ6 · The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for… · the same entry in another collection · chain A against A, TM-score 1.00
- Q06455 · AlphaFold monomer V2.0 prediction for protein CBFA2T1 (Q06455) · a predicted model of the same protein · chain A against A, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06455
- Elsewhere: RCSB PDB 1WQ6 · PDBe 1WQ6 · UniProt Q06455
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.