UniProt Q06210
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (Q06210)
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (UniProt Q06210), EC 2.6.1.16: 26 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 100 pockets. Binding sites, druggability and…
- UniProt
- Q06210
- Protein
- Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
- EC
- 2.6.1.16
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 100 · 8 records with a druggable one
Structures
27 records of Q06210 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2V4M | The isomerase domain of human glutamine-fructose-6-phosphate transaminase 1 (GFPT1) in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 2V4M | The isomerase domain of human glutamine-fructose-6-phosphate transaminase 1 (GFPT1) in complex with… | x-ray diffraction | A, B, C, D | — | — |
| 2ZJ3 | Isomerase domain of human glucose:fructose-6-phosphate amidotransferase | x-ray diffraction | A | — | — |
| 2ZJ3 | Isomerase domain of human GLUCOSE:FRUCTOSE-6-phosphate amidotransferase | x-ray diffraction | A | — | — |
| 2ZJ4 | Isomerase domain of human glucose:fructose-6-phosphate amidotransferase | x-ray diffraction | A | — | — |
| 2ZJ4 | Isomerase domain of human GLUCOSE:FRUCTOSE-6-phosphate amidotransferase | x-ray diffraction | A | — | — |
| 6R4E | Crystal structure of human gfat-1 in complex with glucose-6-phosphate and L-glu | x-ray diffraction | A, B | G6Q | — |
| 6R4F | Crystal structure of human GFAT-1 in complex with Glucose-6-Phosphate | x-ray diffraction | A, B | G6Q | 12 (best 0.87) |
| 6R4F | Crystal structure of human gfat-1 in complex with glucose-6-phosphate | x-ray diffraction | A, B | G6Q | — |
| 6R4G | Crystal structure of human GFAT-1 in complex with UDP-GlcNAc | x-ray diffraction | A, B | UD1, MG, G6Q | 12 (best 0.87) |
| 6R4G | Crystal structure of human gfat-1 in complex with udp-glcnac | x-ray diffraction | A, B | UD1, MG, G6Q | — |
| 6R4H | Crystal structure of human GFAT-1 G451E | x-ray diffraction | A, B | G6Q, GLU | 12 (best 0.87) |
| 6R4H | Crystal structure of human gfat-1 G451E | x-ray diffraction | A, B | G6Q | — |
| 6R4I | Crystal structure of human GFAT-1 G461E | x-ray diffraction | A, B | G6Q, GLU | 15 (best 0.87) |
| 6R4I | Crystal structure of human gfat-1 G461E | x-ray diffraction | A, B | G6Q | — |
| 6R4J | Crystal structure of human GFAT-1 G451E in complex with UDP-GlcNAc | x-ray diffraction | A, B | UD1, MG, G6Q, GLU | 11 (best 0.87) |
| 6R4J | Crystal structure of human gfat-1 G451E in complex with udp-glcnac | x-ray diffraction | A, B | UD1, MG, G6Q | — |
| 6SVM | Crystal structure of human gfat-1 in complex with glucose-6-phosphate, L-glu, and udp-galnac | x-ray diffraction | A, B | G6Q, UD2, MG | — |
| 6SVO | Crystal structure of human GFAT-1 in complex with Glucosamine-6-Phosphate and L-Glu | x-ray diffraction | A, B | AGP, GLU | 15 (best 0.86) |
| 6SVO | Crystal structure of human gfat-1 in complex with glucosamine-6- phosphate and L-glu | x-ray diffraction | A, B | AGP | — |
| 6SVP | Crystal structure of human GFAT-1 in complex with Glucose-6-Phosphate, L-Glu, and UDP-GlcNAc | x-ray diffraction | A, B | UD1, MG, G6Q, GLU | 10 (best 0.87) |
| 6SVP | Crystal structure of human gfat-1 in complex with glucose-6-phosphate, L-glu, and udp-glcnac | x-ray diffraction | A, B | UD1, MG, G6Q | — |
| 6SVQ | Crystal structure of human GFAT-1 G461E after UDP-GlcNAc soaking | x-ray diffraction | A, B | G6Q, GLU | 13 (best 0.87) |
| 6SVQ | Crystal structure of human gfat-1 G461E after udp-glcnac soaking | x-ray diffraction | A, B | G6Q | — |
| 6ZMJ | Crystal structure of human gfat-1 R203H | x-ray diffraction | A, B | G6Q | — |
| 6ZMK | Crystal structure of human gfat-1 L405R | x-ray diffraction | A, B | G6Q | — |
| Q06210 | AlphaFold monomer V2.0 prediction for glutamine--fructose-6-phosphate aminotransferase… | predicted | A | — | — |
Ligands
Experiment against prediction
- 2V4M chain D against the predicted model Q06210: TM-score 1.00, RMSD 0.27 Å
- 2V4M chain D against the predicted model Q06210: TM-score 1.00, RMSD 0.27 Å
- 2V4M chain B against the predicted model Q06210: TM-score 1.00, RMSD 0.33 Å
- 2V4M chain B against the predicted model Q06210: TM-score 1.00, RMSD 0.33 Å
- 2V4M chain C against the predicted model Q06210: TM-score 1.00, RMSD 0.34 Å
- 2V4M chain C against the predicted model Q06210: TM-score 1.00, RMSD 0.34 Å
- 6R4J chain B against the predicted model Q06210: TM-score 1.00, RMSD 0.45 Å
- 6R4J chain B against the predicted model Q06210: TM-score 1.00, RMSD 0.45 Å
- 6R4H chain B against the predicted model Q06210: TM-score 1.00, RMSD 0.46 Å
- 6R4H chain B against the predicted model Q06210: TM-score 1.00, RMSD 0.46 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.