UniProt Q05B79
DEAH (Asp-Glu-Ala-His) box polypeptide 36 (Q05B79)
DEAH (Asp-Glu-Ala-His) box polypeptide 36 (UniProt Q05B79): 8 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 45 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q05B79
- Protein
- DEAH (Asp-Glu-Ala-His) box polypeptide 36
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 45 · 4 records with a druggable one
Structures
9 records of Q05B79 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VHA | DHX36 with an N-terminal truncation | x-ray diffraction | A | — | 10 (best 0.83) |
| 5VHA | DHX36 with an N-terminal truncation | x-ray diffraction | A | — | — |
| 5VHC | DHX36 with an N-terminal truncation bound to ADP-BeF3 | x-ray diffraction | D | MG, BEF, ADP | 8 (best 0.82) |
| 5VHC | DHX36 with an N-terminal truncation bound to ADP-BEF3 | x-ray diffraction | D | MG, BEF, ADP | — |
| 5VHD | DHX36 with an N-terminal truncation bound to ADP-AlF4 | x-ray diffraction | D | ADP, ALF | 9 (best 0.80) |
| 5VHD | DHX36 with an N-terminal truncation bound to ADP-ALF4 | x-ray diffraction | D | ADP, ALF | — |
| 5VHE | DHX36 in complex with the c-Myc G-quadruplex | x-ray diffraction | A | K | 18 (best 0.88) |
| 5VHE | DHX36 in complex with the C-myc G-quadruplex | x-ray diffraction | A | — | — |
| Q05B79 | AlphaFold monomer V2.0 prediction for ATP-dependent DNA/RNA helicase DHX36 (Q05B79) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5VHD chain D against the predicted model Q05B79: TM-score 0.99, RMSD 1.04 Å
- 5VHD chain D against the predicted model Q05B79: TM-score 0.99, RMSD 1.04 Å
- 5VHC chain D against the predicted model Q05B79: TM-score 0.99, RMSD 1.15 Å
- 5VHC chain D against the predicted model Q05B79: TM-score 0.99, RMSD 1.15 Å
- 5VHA chain A against the predicted model Q05B79: TM-score 0.98, RMSD 1.34 Å
- 5VHA chain A against the predicted model Q05B79: TM-score 0.98, RMSD 1.34 Å
- 5VHE chain A against the predicted model Q05B79: TM-score 0.77, RMSD 5.73 Å
- 5VHE chain A against the predicted model Q05B79: TM-score 0.77, RMSD 5.73 Å
Elsewhere
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