UniProt Q04721
Neurogenic locus notch homolog protein 2 (Q04721)
Neurogenic locus notch homolog protein 2 (UniProt Q04721): 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q04721
- Protein
- Neurogenic locus notch homolog protein 2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 11 · 1 record with a druggable one
Structures
5 records of Q04721 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2OO4 | Structure of LNR-HD (Negative Regulatory Region) from human Notch 2 | x-ray diffraction | A, B | — | — |
| 2OO4 | Structure of lnr-hd (negative regulatory region) from human notch 2 | x-ray diffraction | A, B | — | — |
| 5MWB | Human Notch-2 EGF11-13 | x-ray diffraction | A | BGC, XYP, FUC, CA | — |
| 5MWB | Human notch-2 EGF11-13 | x-ray diffraction | A | BGC, XYP, FUC, CA | — |
| Q04721 | AlphaFold monomer V2.0 prediction for neurogenic locus notch homolog protein 2 (Q04721) | predicted | A | — | 11 (best 0.55) |
Ligands
Experiment against prediction
- 2OO4 chain A against the predicted model Q04721: TM-score 0.96, RMSD 1.32 Å
- 2OO4 chain A against the predicted model Q04721: TM-score 0.96, RMSD 1.32 Å
- 5MWB chain A against the predicted model Q04721: TM-score 0.77, RMSD 2.20 Å
- 5MWB chain A against the predicted model Q04721: TM-score 0.77, RMSD 2.20 Å
Elsewhere
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