UniProt Q04477
Kinetochore protein SPC24 (Q04477)
Kinetochore protein SPC24 (UniProt Q04477): 12 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q04477
- Protein
- Kinetochore protein SPC24
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 10 · 2 records with a druggable one
Structures
13 records of Q04477 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FTX | Crystal structure of the yeast kinetochore Spc24/Spc25 globular domain | x-ray diffraction | B | — | — |
| 2FTX | Crystal structure of the yeast kinetochore SPC24/SPC25 globular domain | x-ray diffraction | B | — | — |
| 2FV4 | NMR solution structure of the yeast kinetochore Spc24/Spc25 globular domain | solution nmr | B | — | — |
| 2FV4 | NMR solution structure of the yeast kinetochore SPC24/SPC25 globular domain | solution nmr | B | — | — |
| 4GEQ | Crystal structure of the Spc24-Spc25/Cnn1 binding interface | x-ray diffraction | B, D | — | — |
| 4GEQ | Crystal structure of the SPC24-SPC25/CNN1 binding interface | x-ray diffraction | B, D | — | — |
| 5T6J | Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly | x-ray diffraction | A | — | — |
| 5T6J | Structure of the mind complex shows a regulatory focus of yeast kinetochore assembly | x-ray diffraction | A | — | — |
| 5TCS | Crystal structure of a dwarf NDC80 tetramer | x-ray diffraction | C | — | — |
| 5TD8 | Crystal structure of an Extended Dwarf Ndc80 Complex | x-ray diffraction | C | — | 4 (best 0.68) |
| 5TD8 | Crystal structure of an extended dwarf NDC80 complex | x-ray diffraction | C | — | — |
| 8V11 | Structure of a Saccharomyces cerevisiae Ipl1 peptide Bound to dwarf Ndc80 complex | x-ray diffraction | C, G | — | 6 (best 0.76) |
| Q04477 | AlphaFold monomer V2.0 prediction for kinetochore protein SPC24 (Q04477) | predicted | A | — | — |
Experiment against prediction
- 2FTX chain B against the predicted model Q04477: TM-score 0.96, RMSD 0.90 Å
- 2FTX chain B against the predicted model Q04477: TM-score 0.96, RMSD 0.90 Å
- 5T6J chain A against the predicted model Q04477: TM-score 0.94, RMSD 0.82 Å
- 5T6J chain A against the predicted model Q04477: TM-score 0.94, RMSD 0.82 Å
- 4GEQ chain D against the predicted model Q04477: TM-score 0.89, RMSD 1.27 Å
- 4GEQ chain D against the predicted model Q04477: TM-score 0.89, RMSD 1.27 Å
- 4GEQ chain B against the predicted model Q04477: TM-score 0.86, RMSD 1.70 Å
- 4GEQ chain B against the predicted model Q04477: TM-score 0.86, RMSD 1.70 Å
- 2FV4 chain B against the predicted model Q04477: TM-score 0.70, RMSD 2.20 Å
- 2FV4 chain B against the predicted model Q04477: TM-score 0.70, RMSD 2.20 Å
Elsewhere
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