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UniProt Q02795

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1 (Q02795)

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1 (UniProt Q02795), EC 2.4.99.18: 7 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 25 pockets. Binding sites, druggability…

UniProt
Q02795
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1
EC
2.4.99.18
Experimental structures
7
Predicted models
1
Ligands
7
Pockets
25 · 4 records with a druggable one

Structures

8 records of Q02795 in the MolNFT archive: 7 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6C26The Cryo-EM structure of a eukaryotic oligosaccharyl transferase complexelectron microscopyCBMA, EGY6 (best 0.76)
6C26The cryo-EM structure of a eukaryotic oligosaccharyl transferase complexelectron microscopyCBMA, EGY—
6EZNCryo-EM structure of the yeast oligosaccharyltransferase (OST) complexelectron microscopyHMAN, PTY, CPL6 (best 0.77)
6EZNCryo-EM structure of the yeast oligosaccharyltransferase (ost) complexelectron microscopyHMAN, PTY, CPL—
7OCICryo-EM structure of yeast Ost6p containing oligosaccharyltransferase complexelectron microscopyHMAN, AJP, PEE7 (best 0.74)
7OCICryo-EM structure of yeast OST6P containing oligosaccharyltransferase complexelectron microscopyHMAN, PEE—
8AGBStructure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide boundelectron microscopyFMAN, PTY, CPL6 (best 0.77)
Q02795AlphaFold monomer V2.0 prediction for dolichyl- diphosphooligosaccharide--protein…predictedA——

Ligands

  • MAN · alpha-D-mannopyranose · in 5 records
  • CPL · 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine · in 3 records
  • PTY · Phosphatidylethanolamine · in 3 records
  • BMA · beta-D-mannopyranose · in 2 records
  • EGY · (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium · in 2 records
  • PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · in 2 records
  • AJP · Digitonin · in 1 record

Experiment against prediction

Elsewhere

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