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Ligand · EGY

EGY · (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium

EGY, (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium (C33 H67 N O8 P +1, 636.9 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every…

Component
EGY
Formula
C33 H67 N O8 P +1
Class
ligand
Structures
3
PDB entries
3

Binding sites

EGY in 3 structures; the first of them:

  • 6C26 · The cryo-EM structure of a eukaryotic oligosaccharyl transferase complex · EGY A801 · binds ILE37, SER41, ARG112, ASN113, LEU117, LEU121, TYR303
  • 6S7O · Cryo-EM structure of human oligosaccharyltransferase complex ost-a · EGY A815 · binds LYS19, LEU20, LEU23, SER24, VAL28, ILE129, TYR132, HIS133 and 4 more
  • 6S7T · Cryo-EM structure of human oligosaccharyltransferase complex ost-B · EGY A913 · binds PHE85, VAL92, ILE93, PHE95, SER97, ASP168, PHE172

Residues it binds most

PHE 20, LEU 19, ILE 18, SER 16, TYR 13, VAL 13, ARG 13, MET 10, ASN 8, THR 7 (residue and the binding sites it lines).

Found with

  • BMA · beta-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • KZB · (2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S}, 9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13, 18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol
  • MG · Magnesium ion
  • MAN · alpha-D-mannopyranose
  • 0K3 · (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl dihydrogen phosphate
  • KZE · [(3~{R},6~{Z},10~{Z},14~{Z},18~{Z})-3,7,11,15,19,23-hexamethyltetracosa-6,10,14,18,22-pentaenyl] dihydrogen phosphate

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