UniProt Q01668
Voltage-dependent L-type calcium channel subunit alpha-1D (Q01668)
Voltage-dependent L-type calcium channel subunit alpha-1D (UniProt Q01668): 6 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q01668
- Protein
- Voltage-dependent L-type calcium channel subunit alpha-1D
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 28 · 2 records with a druggable one
Structures
7 records of Q01668 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3LV3 | Crystal structure of HLA-B*2705 complexed with a peptide derived from the human voltage-dependent… | x-ray diffraction | C | — | — |
| 3LV3 | Crystal structure of HLA-B*2705 complexed with a peptide derived from the human voltage-dependent… | x-ray diffraction | C | — | — |
| 7UHF | Human L-type voltage-gated calcium channel CAV1.3 in the presence of cinnarizine at 3.1 ångström… | electron microscopy | A | N90, NAG, CA, Y01, 3PE | — |
| 7UHG | Human L-type voltage-gated calcium channel Cav1.3 at 3.0 Angstrom resolution | electron microscopy | A | NAG, CA, CLR, 3PE | 15 (best 0.85) |
| 7UHG | Human L-type voltage-gated calcium channel CAV1.3 at 3.0 ångström resolution | electron microscopy | A | NAG, CA, CLR, 3PE | — |
| 8E59 | Human L-type voltage-gated calcium channel Cav1.3 in the presence of Amiodarone at 3.1 Angstrom… | electron microscopy | A | BBI, CA, 3PE | 13 (best 0.85) |
| Q01668 | AlphaFold monomer V2.0 prediction for voltage-dependent L-type calcium channel subunit alpha-1D… | predicted | A | — | — |
Ligands
- 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 4 records
- CA · Calcium ion · in 4 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records
- CLR · Cholesterol · in 2 records
- BBI · (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone · in 1 record
- N90 · 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine · in 1 record
- Y01 · Cholesterol hemisuccinate · in 1 record
Experiment against prediction
- 8E59 chain A against the predicted model Q01668: TM-score 0.98, RMSD 1.52 Å
- 7UHG chain A against the predicted model Q01668: TM-score 0.98, RMSD 1.54 Å
- 7UHG chain A against the predicted model Q01668: TM-score 0.98, RMSD 1.54 Å
- 7UHF chain A against the predicted model Q01668: TM-score 0.98, RMSD 1.65 Å
- 3LV3 chain C against the predicted model Q01668: TM-score 0.34, RMSD 1.04 Å
- 3LV3 chain C against the predicted model Q01668: TM-score 0.34, RMSD 1.04 Å
Elsewhere
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