UniProt P9WPG7
Phosphatidylinositol phosphate synthase (P9WPG7)
Phosphatidylinositol phosphate synthase (UniProt P9WPG7): 4 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WPG7
- Protein
- Phosphatidylinositol phosphate synthase
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 1 · 0 records with a druggable one
Structures
5 records of P9WPG7 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6H59 | Crystal structure of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase (PgsA1)… | x-ray diffraction | A, B | MG, SO4, FQT, OLB | — |
| 6H59 | Crystal structure of mycobacterium tuberculosis phosphatidylinositol phosphate synthase (PGSA1)… | x-ray diffraction | A, B | MG, SO4, FQT, OLB | — |
| 6H5A | Crystal structure of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase (PgsA1) in… | x-ray diffraction | A, B | MN, LFA, SO4 | — |
| 6H5A | Crystal structure of mycobacterium tuberculosis phosphatidylinositol phosphate synthase (PGSA1) in… | x-ray diffraction | A, B | MN, LFA, SO4 | — |
| P9WPG7 | AlphaFold monomer V2.0 prediction for phosphatidylinositol phosphate synthase (P9WPG7) | predicted | A | — | 1 (best 0.45) |
Ligands
- SO4 · Sulfate ion · in 4 records
- FQT · [(2~{S})-3-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-azanyl-2-oxidanylidene-1,4-dihydropyrimidin-3-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-2-hexanoyloxy-propyl] hexanoate · in 2 records
- LFA · Eicosane · in 2 records
- MG · Magnesium ion · in 2 records
- MN · Manganese (II) ion · in 2 records
- OLB · (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · in 2 records
Experiment against prediction
- 6H59 chain A against the predicted model P9WPG7: TM-score 0.97, RMSD 0.89 Å
- 6H59 chain A against the predicted model P9WPG7: TM-score 0.97, RMSD 0.89 Å
- 6H59 chain B against the predicted model P9WPG7: TM-score 0.97, RMSD 0.94 Å
- 6H59 chain B against the predicted model P9WPG7: TM-score 0.97, RMSD 0.94 Å
- 6H5A chain A against the predicted model P9WPG7: TM-score 0.94, RMSD 1.44 Å
- 6H5A chain A against the predicted model P9WPG7: TM-score 0.94, RMSD 1.44 Å
- 6H5A chain B against the predicted model P9WPG7: TM-score 0.93, RMSD 1.00 Å
- 6H5A chain B against the predicted model P9WPG7: TM-score 0.93, RMSD 1.00 Å
Elsewhere
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