UniProt P82974
1,6-anhydro-N-acetylmuramyl-L-alanine amidase ampd (P82974)
1,6-anhydro-N-acetylmuramyl-L-alanine amidase ampd (UniProt P82974), EC 3.5.1.28: 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 53 pockets. Binding sites, druggability and experiment against…
- UniProt
- P82974
- Protein
- 1,6-anhydro-N-acetylmuramyl-L-alanine amidase ampd
- EC
- 3.5.1.28
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 53 · 12 records with a druggable one
Structures
13 records of P82974 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1J3G | Solution structure of Citrobacter Freundii AmpD | solution nmr | A | ZN | 1 (best 0.58) |
| 1J3G | Solution structure of citrobacter freundii ampd | solution nmr | A | ZN | 1 (best 0.58) |
| 2Y28 | crystal structure of Se-Met AmpD derivative | x-ray diffraction | A, B, C | ZN | 6 (best 0.54) |
| 2Y28 | Crystal structure of se-met ampd derivative | x-ray diffraction | A, B, C | ZN | 6 (best 0.54) |
| 2Y2B | crystal structure of AmpD in complex with reaction products | x-ray diffraction | A, B, C | AH0, MHI, ZN | 5 (best 0.54) |
| 2Y2B | Crystal structure of ampd in complex with reaction products | x-ray diffraction | A, B, C | AH0, MHI, ZN | 5 (best 0.54) |
| 2Y2C | crystal structure of AmpD Apoenzyme | x-ray diffraction | A, B, C | — | 4 (best 0.53) |
| 2Y2C | Crystal structure of ampd apoenzyme | x-ray diffraction | A, B, C | — | 4 (best 0.53) |
| 2Y2D | crystal structure of AmpD holoenzyme | x-ray diffraction | A, B, C | ZN | 5 (best 0.55) |
| 2Y2D | Crystal structure of ampd holoenzyme | x-ray diffraction | A, B, C | ZN | 5 (best 0.55) |
| 2Y2E | crystal structure of AmpD grown at pH 5.5 | x-ray diffraction | A, B, C | ZN | 5 (best 0.55) |
| 2Y2E | Crystal structure of ampd grown at pH 5.5 | x-ray diffraction | A, B, C | ZN | 5 (best 0.55) |
| P82974 | AlphaFold monomer V2.0 prediction for 1,6-anhydro-N-acetylmuramyl-L- alanine amidase ampd (P82974) | predicted | A | — | 1 (best 0.49) |
Ligands
Experiment against prediction
- 2Y2C chain B against the predicted model P82974: TM-score 0.99, RMSD 0.45 Å
- 2Y2C chain B against the predicted model P82974: TM-score 0.99, RMSD 0.45 Å
- 2Y2B chain A against the predicted model P82974: TM-score 0.99, RMSD 0.45 Å
- 2Y2B chain A against the predicted model P82974: TM-score 0.99, RMSD 0.45 Å
- 2Y2D chain B against the predicted model P82974: TM-score 0.99, RMSD 0.45 Å
- 2Y2D chain B against the predicted model P82974: TM-score 0.99, RMSD 0.45 Å
- 2Y2E chain B against the predicted model P82974: TM-score 0.99, RMSD 0.46 Å
- 2Y2E chain B against the predicted model P82974: TM-score 0.99, RMSD 0.46 Å
- 2Y28 chain B against the predicted model P82974: TM-score 0.99, RMSD 0.46 Å
- 2Y28 chain B against the predicted model P82974: TM-score 0.99, RMSD 0.46 Å
Elsewhere
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