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Ligand · MHI

MHI · L-ala-gamma-D-glu-meso-diaminopimelic acid

MHI, L-ala-gamma-D-glu-meso-diaminopimelic acid (C15 H26 N4 O8, 390.4 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
MHI
Formula
C15 H26 N4 O8
Class
ligand
Structures
7
PDB entries
4

Binding sites

MHI in 7 structures; the first of them:

  • 2Y2B · crystal structure of AmpD in complex with reaction products · MHI A202 · binds ASP20, HIS34, PHE52, ARG71, VAL72, SER73, TRP95, HIS96 and 9 more
  • 3O9P · The structure of the Escherichia coli murein tripeptide binding protein MppA · MHI A516 · binds LYS20, VAL32, GLY33, LEU34, PRO35, ILE37, PHE109, GLU244 and 13 more
  • 4Q6N · Structural analysis of the tripeptide-bound form of Helicobacter pylori Csd4, a… · MHI A501 · binds ARG86, ASN93, ARG94, HIS126, HIS128, ASP129, GLY130, GLY131 and 10 more
  • 8AY0 · Crystal Structure of the peptide binding protein DppE from Bacillus subtilis in complex… · MHI A601 · binds PHE41, ASN42, ASN43, ARG237, TYR253, GLN273, TRP404, LEU408 and 10 more
  • 2Y2B · Crystal structure of ampd in complex with reaction products · MHI A1001 · binds ASP20, HIS34, PHE52, ARG71, VAL72, SER73, TRP95, HIS96 and 9 more
  • 3O9P · The structure of the escherichia COLI murein tripeptide binding protein mppa · MHI A516 · binds LYS20, VAL32, GLY33, LEU34, PRO35, ILE37, PHE109, GLU244 and 13 more
  • 4Q6N · Structural analysis of the tripeptide-bound form of helicobacter pylori CSD4, a… · MHI A501 · binds ARG86, ASN93, ARG94, HIS126, HIS128, ASP129, GLY130, GLY131 and 10 more

Residues it binds most

ARG 9, ASN 9, TYR 5, ASP 9, TRP 9, GLY 6, HIS 4, LEU 7, PHE 7, SER 7 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • AH0 · 2-(2-acetylamino-4-hydroxy-6,8-dioxa-bicyclo[3.2.1]oct-3-yloxy)-propionic acid
  • CA · Calcium ion
  • GOL · Glycerol
  • MG · Magnesium ion
  • EDO · 1,2-ethanediol

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