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UniProt P80078

Glutamate mutase sigma subunit (P80078)

Glutamate mutase sigma subunit (UniProt P80078), EC 5.4.99.1: 12 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 90 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…

UniProt
P80078
Protein
Glutamate mutase sigma subunit
EC
5.4.99.1
Experimental structures
12
Predicted models
1
Ligands
5
Pockets
90 · 12 records with a druggable one

Structures

13 records of P80078 in the MolNFT archive: 12 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
1B1AGlutamate mutase (B12-binding subunit), NMR, minimized average structuresolution nmrA—3 (best 0.54)
1B1AGlutamate mutase (B12-binding subunit), NMR, minimized average structuresolution nmrA—3 (best 0.54)
1CB7Glutamate mutase from clostridium cochlearium reconstituted with methyl-cobalaminx-ray diffractionA, CCOB8 (best 0.86)
1CB7Glutamate mutase from clostridium cochlearium reconstituted with methyl-cobalaminx-ray diffractionA, CCOB8 (best 0.86)
1CCWStructure of the coenzyme B12 dependent enzyme glutamate mutase from clostridium cochleariumx-ray diffractionA, CCNC10 (best 0.86)
1CCWStructure of the coenzyme B12 dependent enzyme glutamate mutase from clostridium cochleariumx-ray diffractionA, CCNC10 (best 0.86)
1I9CGlutamate mutase from clostridium cochlearium: complex with adenosylcobalamin and substratex-ray diffractionA, CB128 (best 0.87)
1I9CGlutamate mutase from clostridium cochlearium: complex with adenosylcobalamin and substratex-ray diffractionA, CB128 (best 0.87)
6H9EStructure of glutamate mutase reconstituted with homo-coenzyme B12x-ray diffractionA, CB12, FWK7 (best 0.86)
6H9EStructure of glutamate mutase reconstituted with homo-coenzyme B12x-ray diffractionA, CB12, FWK7 (best 0.86)
6H9FStructure of glutamate mutase reconstituted with bishomo-coenzyme B12x-ray diffractionA, CB12, 8ZB9 (best 0.86)
6H9FStructure of glutamate mutase reconstituted with bishomo-coenzyme B12x-ray diffractionA, CB12, 8ZB9 (best 0.86)
P80078AlphaFold monomer V2.0 prediction for glutamate mutase sigma subunit (P80078)predictedA——

Ligands

  • B12 · Cobalamin · in 6 records
  • 8ZB · (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-propyl-oxolane-3,4-diol · in 2 records
  • CNC · Cyanocobalamin · in 2 records
  • COB · Co-methylcobalamin · in 2 records
  • FWK · (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-ethyl-oxolane-3,4-diol · in 2 records

Experiment against prediction

Elsewhere

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