UniProt P78310
Coxsackievirus and adenovirus receptor (P78310)
Coxsackievirus and adenovirus receptor (UniProt P78310): 42 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 109 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P78310
- Protein
- Coxsackievirus and adenovirus receptor
- Experimental structures
- 42
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 109 · 19 records with a druggable one
Structures
43 records of P78310 in the MolNFT archive: 42 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EAJ | Dimeric structure of the coxsackie virus and adenovirus receptor D1 domain at 1.35 ångström… | x-ray diffraction | A, B | SO4 | 1 (best 0.62) |
| 1EAJ | Dimeric structure of the coxsackie virus and adenovirus receptor D1 domain at 1.35 ångström… | x-ray diffraction | A, B | SO4 | 1 (best 0.62) |
| 1F5W | Dimeric structure of the coxsackie virus and adenovirus receptor D1 domain | x-ray diffraction | A, B | SO4 | 1 (best 0.61) |
| 1F5W | Dimeric structure of the coxsackie virus and adenovirus receptor D1 domain | x-ray diffraction | A, B | SO4 | 1 (best 0.61) |
| 1JEW | Cryo-EM structure of coxsackievirus B3(M strain) with its cellular receptor, coxsackievirus and… | electron microscopy | R | — | 1 (best 0.42) |
| 1JEW | Cryo-EM structure of coxsackievirus B3(M strain) with its cellular receptor, coxsackievirus and… | electron microscopy | R | — | 1 (best 0.42) |
| 1KAC | Knob domain from adenovirus serotype 12 in complex with domain 1 of its cellular receptor car | x-ray diffraction | B | — | 2 (best 0.43) |
| 1KAC | Knob domain from adenovirus serotype 12 in complex with domain 1 of its cellular receptor car | x-ray diffraction | B | — | 2 (best 0.43) |
| 1P69 | Structural basis for variation in adenovirus affinity for the cellular receptor car (P417S mutant) | x-ray diffraction | B | — | 2 (best 0.64) |
| 1P69 | Structural basis for variation in adenovirus affinity for the cellular receptor car (P417S mutant) | x-ray diffraction | B | — | 2 (best 0.64) |
| 1P6A | Structural basis for variation in adenovirus affinity for the cellular receptor car (S489Y mutant) | x-ray diffraction | B | — | 2 (best 0.44) |
| 1P6A | Structural basis for variation in adenovirus affinity for the cellular receptor car (S489Y mutant) | x-ray diffraction | B | — | 2 (best 0.44) |
| 1RSF | NMR Structure of Monomeric CAR d1 domain | solution nmr | A | — | 1 (best 0.41) |
| 1RSF | NMR structure of monomeric car D1 domain | solution nmr | A | — | 1 (best 0.41) |
| 2J12 | Ad37 fibre head in complex with CAR D1 | x-ray diffraction | B | CA | 2 (best 0.37) |
| 2J12 | AD37 fibre head in complex with car D1 | x-ray diffraction | B | CA | 2 (best 0.37) |
| 2J1K | CAV-2 fibre head in complex with CAR D1 | x-ray diffraction | A, B, G, J, K, O, P, T, V, X, Y, Z | — | 16 (best 0.81) |
| 2J1K | Cav-2 fibre head in complex with car D1 | x-ray diffraction | A, B, G, J, K, O, P, T, V, X, Y, Z | — | 16 (best 0.81) |
| 2NPL | NMR Structure of CARD d2 Domain | solution nmr | X | — | — |
| 2NPL | NMR structure of card D2 domain | solution nmr | X | — | — |
| 2W9L | Canine adenovirus type 2 fibre head in complex with car domain D1 and sialic acid | x-ray diffraction | A, B, G, J, K, O, P, T, V, X, Y, Z | — | 16 (best 0.84) |
| 2W9L | Canine adenovirus type 2 fibre head in complex with car domain D1 and sialic acid | x-ray diffraction | A, B, G, J, K, O, P, T, V, X, Y, Z | — | 16 (best 0.84) |
| 2WBW | Ad37 fibre head in complex with CAR D1 and sialic acid | x-ray diffraction | B | CA | 3 (best 0.64) |
| 2WBW | AD37 fibre head in complex with car D1 and sialic acid | x-ray diffraction | B | CA | 3 (best 0.64) |
| 3J6L | Kinetic and Structural Analysis of Coxsackievirus B3 Receptor Interactions and Formation of the… | electron microscopy | B | SO4 | — |
| 3J6L | Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the… | electron microscopy | B | SO4 | — |
| 3J6M | Kinetic and Structural Analysis of Coxsackievirus B3 Receptor Interactions and Formation of the… | electron microscopy | B | — | — |
| 3J6M | Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the… | electron microscopy | B | — | — |
| 7DPZ | Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR | electron microscopy | K | — | 3 (best 0.77) |
| 7DPZ | Cryo-EM structure of coxsackievirus B1 virion in complex with car | electron microscopy | K | — | — |
| 7DQ1 | Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR at physiological temperature | electron microscopy | K | — | 2 (best 0.76) |
| 7DQ1 | Cryo-EM structure of coxsackievirus B1 virion in complex with car at physiological temperature | electron microscopy | K | — | — |
| 7VXZ | Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | 2 (best 0.79) |
| 7VXZ | Coxsackievirus B3 at PH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | — |
| 7VYK | Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | 3 (best 0.77) |
| 7VYK | Coxsackievirus B3 at PH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | — |
| 7VYL | Coxsackievirus B3 at pH5.5 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | 2 (best 0.80) |
| 7VYL | Coxsackievirus B3 at PH5.5 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | — |
| 7VYM | Coxsackievirus B3 at pH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | 2 (best 0.67) |
| 7VYM | Coxsackievirus B3 at PH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | — |
| 7W14 | Coxsackievirus B3 at pH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | 1 (best 0.80) |
| 7W14 | Coxsackievirus B3 at PH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for… | electron microscopy | E | — | — |
| P78310 | AlphaFold monomer V2.0 prediction for coxsackievirus and adenovirus receptor (P78310) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2J1K chain O against the predicted model P78310: TM-score 0.97, RMSD 1.09 Å
- 2J1K chain O against the predicted model P78310: TM-score 0.97, RMSD 1.09 Å
- 2W9L chain O against the predicted model P78310: TM-score 0.96, RMSD 1.14 Å
- 2W9L chain O against the predicted model P78310: TM-score 0.96, RMSD 1.14 Å
- 2W9L chain A against the predicted model P78310: TM-score 0.96, RMSD 1.21 Å
- 2W9L chain A against the predicted model P78310: TM-score 0.96, RMSD 1.21 Å
- 2J1K chain T against the predicted model P78310: TM-score 0.96, RMSD 1.21 Å
- 2J1K chain T against the predicted model P78310: TM-score 0.96, RMSD 1.21 Å
- 2J1K chain A against the predicted model P78310: TM-score 0.96, RMSD 1.22 Å
- 2J1K chain A against the predicted model P78310: TM-score 0.96, RMSD 1.22 Å
Elsewhere
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