UniProt P76143
Aldolase lsrF (P76143)
Aldolase lsrF (UniProt P76143), EC 4.1.2.-: 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 160 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P76143
- Protein
- Aldolase lsrF
- EC
- 4.1.2.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 160 · 8 records with a druggable one
Structures
9 records of P76143 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3GKF | Crystal Structure of E. coli LsrF | x-ray diffraction | O, L, M, N, K, F, I, H, G, J, S, P, Q, R, T, E, B, C, D, A | — | 20 (best 0.70) |
| 3GKF | Crystal structure of E. COLI lsrf | x-ray diffraction | O, L, M, N, K, F, I, H, G, J, S, P, Q, R, T, E, B, C, D, A | — | 20 (best 0.70) |
| 3GLC | Crystal Structure of E. coli LsrF in complex with Ribose-5-phosphate | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | R5P | 20 (best 0.69) |
| 3GLC | Crystal structure of E. COLI lsrf in complex with ribose-5-phosphate | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | R5P | 20 (best 0.69) |
| 3GND | Crystal Structure of E. coli LsrF in complex with Ribulose-5-phosphate | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | 5RP | 20 (best 0.71) |
| 3GND | Crystal structure of E. COLI lsrf in complex with ribulose-5-phosphate | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T | 5RP | 20 (best 0.71) |
| 4P2V | Structure of the AI-2 processing enzyme LsrF in complex with the product of the LsrG reaction P-HPD | x-ray diffraction | A, B, C, D, E, F, G, H, I, K | 26T | 20 (best 0.70) |
| 4P2V | Structure of the ai-2 processing enzyme lsrf in complex with the product of the lsrg reaction P-hpd | x-ray diffraction | A, B, C, D, E, F, G, H, I, K | 26T | 20 (best 0.70) |
| P76143 | AlphaFold monomer V2.0 prediction for 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase (P76143) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3GND chain A against the predicted model P76143: TM-score 1.00, RMSD 0.33 Å
- 3GND chain A against the predicted model P76143: TM-score 1.00, RMSD 0.33 Å
- 3GLC chain A against the predicted model P76143: TM-score 1.00, RMSD 0.37 Å
- 3GLC chain A against the predicted model P76143: TM-score 1.00, RMSD 0.37 Å
- 3GKF chain O against the predicted model P76143: TM-score 1.00, RMSD 0.40 Å
- 3GKF chain O against the predicted model P76143: TM-score 1.00, RMSD 0.40 Å
- 4P2V chain A against the predicted model P76143: TM-score 0.99, RMSD 0.49 Å
- 4P2V chain A against the predicted model P76143: TM-score 0.99, RMSD 0.49 Å
- 4P2V chain F against the predicted model P76143: TM-score 0.99, RMSD 0.58 Å
- 4P2V chain F against the predicted model P76143: TM-score 0.99, RMSD 0.58 Å
Elsewhere
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