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UniProt P68372

Tubulin beta-4B chain (P68372)

Tubulin beta-4B chain (UniProt P68372): 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 83 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P68372
Protein
Tubulin beta-4B chain
Experimental structures
4
Predicted models
1
Ligands
3
Pockets
83 · 5 records with a druggable one

Structures

5 records of P68372 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
8I7OIn situ structure of axonemal doublet microtubules in mouse sperm with 16-nm repeatelectron microscopyAF, AH, BF, BH, CF, CH, CJ, DD, DF, DH, ED, EF, EH, FD, FF, FH, GD, GF, GH, HD, HF, HH, IF, IH, JD, JF, JH, KD, KF, KH, LD, LF, LH, MF, MH, ND, NF, NH, OD, OF, OH, PF, PH, QF, QH, RF, RH, RJ, SF, SH, SJ, TF, TH, TJ, UD, UF, UH, VD, VF, VH, WF, WHGTP19 (best 0.90)
8I7RIn situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeatelectron microscopyAB, AD, AF, AH, AJ, AL, BB, BD, BF, BH, BJ, BL, CB, CD, CF, CH, CJ, CL, DB, DD, DF, DH, DJ, DL, EB, ED, EF, EH, EJ, EL, FB, FD, FF, FH, FJ, FL, GB, GD, GF, GH, GJ, GL, HB, HD, HF, HH, HJ, HL, IB, ID, IF, IH, IJ, IL, JB, JD, JF, JH, JJ, JL, KB, KD, KF, KH, KJ, KL, LB, LD, LF, LH, LJ, LL, MB, MD, MF, MH, MJ, ML, NB, ND, NF, NH, NJ, NL, OB, OD, OF, OH, OJ, OL, PB, PD, PF, PH, PJ, PL, QB, QD, QF, QH, QJ, QL, RB, RD, RF, RH, RJ, RL, SB, SD, SF, SH, SJ, SL, TB, TD, TF, TH, TJ, TL, TN, UB, UD, UF, UH, UJ, UL, VB, VD, VF, VH, VJ, VL, WB, WD, WF, WH, WJ, WLGTP20 (best 0.90)
8IYJCryo-EM structure of the 48-nm repeat doublet microtubule from mouse spermelectron microscopyAB, AD, AF, AH, AJ, AL, AN, AP, BB, BD, BF, BH, BJ, BL, BN, BP, CB, CD, CF, CH, CJ, CL, CN, CP, DB, DD, DF, DH, DJ, DL, DN, DP, EB, ED, EF, EH, EJ, EL, EN, FB, FD, FF, FH, FJ, FL, FN, GB, GD, GF, GH, GJ, GL, GN, HB, HD, HF, HH, HJ, HL, HN, HP, IB, ID, IF, IH, IJ, IL, IN, IP, JB, JD, JF, JH, JJ, JL, JN, JP, KB, KD, KF, KH, KJ, KL, KN, KP, LB, LD, LF, LH, LJ, LL, LN, LP, MB, MD, MF, MH, MJ, ML, MN, MP, NB, ND, NF, NH, NJ, NL, NN, NP, OB, OD, OF, OH, OJ, OL, ON, OP, PB, PD, PF, PH, PJ, PL, PN, PP, QB, QD, QF, QH, QJ, QL, QN, QP, RD, RF, RH, RJ, RL, RN, RP, SB, SD, SF, SH, SJ, SL, SN, TB, TD, TF, TH, TJ, TL, TN, UB, UD, UF, UH, UJ, UL, UN, VB, VD, VF, VH, VJ, VL, VN, WB, WD, WF, WH, WJ, WL, WN, WPGDP, GTP, MG17 (best 0.89)
8TO048-nm repeating structure of doublets from mouse sperm flagellaelectron microscopyO, Q, S, U, W, Y, o, q, s, u, w, y, BR, BT, BV, BX, BZ, AV, AX, Ak, Am, Ao, Aq, As, Au, Aw, A4, A6, A8, A0, BB, BD, BF, BN, BP, CY, Cb, Cd, Cf, Ch, Bb, Bd, Bf, Bh, Bj, Bl, Bn, Bs, Bu, Bw, By, B1, B3, B7, B9, CA, CC, CE, CG, CI, CM, CO, CQ, CS, CU, CW, Di, Dk, Dm, Dq, Ds, Cj, Cl, Cn, Cr, Ct, Cv, Cx, Cz, C2, C4, C7, C9, DA, DC, DE, DG, DI, DL, DN, DP, DR, DT, DV, DX, Dc, De, Dg, Er, Et, Ev, Ex, Du, Dw, Dy, D1, D6, D8, D0, EB, ED, EF, EK, EM, EO, EQ, ES, EU, EZ, Eb, Ed, Ef, Eh, Ej, Ep, E4, E6, E8, E0, FB, FD, FH, FJ, FL, FN, FP, FR, FV, FX, AN, FZ, Fb, Fd, Ff, AP, Bq, Da, En, E2, FF, FT, AR, AT—20 (best 0.77)
P68372AlphaFold monomer V2.0 prediction for tubulin beta-4B chain (P68372)predictedA—7 (best 0.59)

Ligands

  • GTP · Guanosine-5'-triphosphate · in 3 records
  • GDP · Guanosine-5'-diphosphate · in 1 record
  • MG · Magnesium ion · in 1 record

Experiment against prediction

Elsewhere

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