UniProt P68371
Tubulin beta-4B chain (P68371)
Tubulin beta-4B chain (UniProt P68371): 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P68371
- Protein
- Tubulin beta-4B chain
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 54 · 4 records with a druggable one
Structures
4 records of P68371 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UN1 | 8-nm repeat of the human sperm tip singlet microtubule | electron microscopy | AB, AD, AF, BA, BD, BF, CB, CD, CF, DB, DD, DF, EB, ED, EF, FD, FF, FH, GD, GF, GH, HD, HF, HH, ID, IF, IH, JD, JF, KD, KF, KH, LB, LD, LF, MB, MD, MF | GDP, GTP, MG | 20 (best 0.85) |
| 7UNG | 48-nm repeat of the human respiratory doublet microtubule | electron microscopy | AB, AD, AF, AH, AJ, AL, BB, BD, BF, BH, BJ, BL, CB, CD, CF, CH, CJ, CL, DB, DD, DF, DH, DJ, DL, EB, ED, EF, EH, EJ, EL, EN, FB, FD, FF, FH, FJ, FL, FN, GB, GD, GF, GH, GJ, GL, GN, HB, HD, HF, HH, HJ, HL, HN, IB, ID, IF, IH, IJ, IL, IN, JB, JD, JF, JH, JJ, JL, JN, KB, KD, KF, KH, KJ, KL, KN, LB, LD, LF, LH, LJ, LL, LN, MB, MD, MF, MH, MJ, ML, MN, NB, ND, NF, NH, NJ, NL, NN, OB, OD, OF, OH, OJ, OL, ON, PD, PF, PH, PJ, PL, PN, QD, QF, QH, QJ, QL, QN, RD, RF, RH, RJ, RL, RN, SD, SF, SH, SJ, SL, SN, TD, TF, TH, TJ, TL, TN, TP, UD, UF, UH, UJ, UL, UN, UP, VD, VF, VH, VJ, VL, VN, VP, WD, WF, WH, WJ, WL, WN, WP | GDP, GTP, MG | 18 (best 0.88) |
| 8SH7 | TUBB4B and TUBA1A Heterodimer from Human Respiratory Doublet Microtubules | electron microscopy | B | GTP, MG, GDP | 9 (best 0.84) |
| P68371 | AlphaFold monomer V2.0 prediction for tubulin beta-4B chain (P68371) | predicted | A | — | 7 (best 0.65) |
Ligands
Experiment against prediction
- 7UNG chain BJ against the predicted model P68371: TM-score 0.97, RMSD 1.25 Å
- 7UNG chain BB against the predicted model P68371: TM-score 0.97, RMSD 1.25 Å
- 7UNG chain BF against the predicted model P68371: TM-score 0.97, RMSD 1.27 Å
- 7UNG chain CB against the predicted model P68371: TM-score 0.97, RMSD 1.30 Å
- 8SH7 chain B against the predicted model P68371: TM-score 0.97, RMSD 1.32 Å
- 7UNG chain BD against the predicted model P68371: TM-score 0.97, RMSD 1.31 Å
- 7UNG chain BH against the predicted model P68371: TM-score 0.97, RMSD 1.32 Å
- 7UNG chain BL against the predicted model P68371: TM-score 0.97, RMSD 1.32 Å
- 7UNG chain CJ against the predicted model P68371: TM-score 0.97, RMSD 1.33 Å
- 7UNG chain CL against the predicted model P68371: TM-score 0.97, RMSD 1.33 Å
Elsewhere
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