UniProt P62593
Beta-lactamase TEM (P62593)
Beta-lactamase TEM (UniProt P62593), EC 3.5.2.6: 125 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62593
- Protein
- Beta-lactamase TEM
- EC
- 3.5.2.6
- Experimental structures
- 125
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 26 · 2 records with a druggable one
Structures
126 records of P62593 in the MolNFT archive: 125 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AXB | Tem-1 beta-lactamase from escherichia COLI inhibited with an acylation transition state analog | x-ray diffraction | A | — | — |
| 1AXB | Tem-1 beta-lactamase from escherichia COLI inhibited with an acylation transition state analog | x-ray diffraction | A | — | — |
| 1BT5 | Crystal structure of the imipenem inhibited tem-1 beta-lactamase from escherichia COLI | x-ray diffraction | A | — | — |
| 1BT5 | Crystal structure of the imipenem inhibited tem-1 beta-lactamase from escherichia COLI | x-ray diffraction | A | — | — |
| 1BTL | Crystal structure of escherichia COLI TEM1 beta-lactamase at 1.8 ångströms resolution | x-ray diffraction | A | — | — |
| 1BTL | Crystal structure of escherichia COLI TEM1 beta-lactamase at 1.8 ångströms resolution | x-ray diffraction | A | — | — |
| 1CK3 | N276D mutant of escherichia COLI tem-1 beta-lactamase | x-ray diffraction | A | — | — |
| 1CK3 | N276D mutant of escherichia COLI tem-1 beta-lactamase | x-ray diffraction | A | — | — |
| 1ERM | X-ray crystal structure of tem-1 beta lactamase in complex with a designed boronic acid inhibitor… | x-ray diffraction | A | — | — |
| 1ERM | X-ray crystal structure of tem-1 beta lactamase in complex with a designed boronic acid inhibitor… | x-ray diffraction | A | — | — |
| 1ERO | X-ray crystal structure of tem-1 beta lactamase in complex with a designed boronic acid inhibitor… | x-ray diffraction | A | — | — |
| 1ERO | X-ray crystal structure of tem-1 beta lactamase in complex with a designed boronic acid inhibitor… | x-ray diffraction | A | — | — |
| 1ERQ | X-ray crystal structure of tem-1 beta lactamase in complex with a designed boronic acid inhibitor… | x-ray diffraction | A | — | — |
| 1ERQ | X-ray crystal structure of tem-1 beta lactamase in complex with a designed boronic acid inhibitor… | x-ray diffraction | A | — | — |
| 1ESU | S235A mutant of TEM1 beta-lactamase | x-ray diffraction | A | — | — |
| 1ESU | S235A mutant of TEM1 beta-lactamase | x-ray diffraction | A | — | — |
| 1FQG | Molecular structure of the acyl-enzyme intermediate in tem-1 beta-lactamase | x-ray diffraction | A | — | — |
| 1FQG | Molecular structure of the acyl-enzyme intermediate in tem-1 beta- lactamase | x-ray diffraction | A | — | — |
| 1JTD | Crystal structure of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase | x-ray diffraction | A | — | — |
| 1JTD | Crystal structure of beta-lactamase inhibitor protein-II in complex with tem-1 beta-lactamase | x-ray diffraction | A | — | — |
| 1JTG | Crystal structure of tem-1 beta-lactamase / beta-lactamase inhibitor protein complex | x-ray diffraction | A, C | — | — |
| 1JTG | Crystal structure of tem-1 beta-lactamase / beta-lactamase inhibitor protein complex | x-ray diffraction | A, C | — | — |
| 1JVJ | Crystal structure of N132A mutant of tem-1 beta-lactamase in complex with a… | x-ray diffraction | A | — | — |
| 1JVJ | Crystal structure of N132A mutant of tem-1 beta-lactamase in complex with a… | x-ray diffraction | A | — | — |
| 1JWP | Structure of M182T mutant of TEM-1 beta-lactamase | x-ray diffraction | A | — | — |
| 1JWP | Structure of M182T mutant of tem-1 beta-lactamase | x-ray diffraction | A | — | — |
| 1JWV | Crystal structure of G238A mutant of TEM-1 beta-lactamase in complex with a boronic acid inhibitor… | x-ray diffraction | A | — | — |
| 1JWV | Crystal structure of G238A mutant of tem-1 beta-lactamase in complex with a boronic acid inhibitor… | x-ray diffraction | A | — | — |
| 1JWZ | Crystal structure of TEM-64 beta-lactamase in complex with a boronic acid inhibitor (105) | x-ray diffraction | A | — | — |
| 1JWZ | Crystal structure of tem-64 beta-lactamase in complex with a boronic acid inhibitor (105) | x-ray diffraction | A | — | — |
| 1LHY | Crystal structure of TEM-30 beta-Lactamase at 2.0 Angstrom | x-ray diffraction | A | — | — |
| 1LHY | Crystal structure of tem-30 beta-lactamase at 2.0 ångström | x-ray diffraction | A | — | — |
| 1LI0 | Crystal structure of TEM-32 beta-Lactamase at 1.6 Angstrom | x-ray diffraction | A | — | — |
| 1LI0 | Crystal structure of tem-32 beta-lactamase at 1.6 ångström | x-ray diffraction | A | — | — |
| 1LI9 | Crystal structure of TEM-34 beta-Lactamase at 1.5 Angstrom | x-ray diffraction | A | — | — |
| 1LI9 | Crystal structure of tem-34 beta-lactamase at 1.5 ångström | x-ray diffraction | A | — | — |
| 1M40 | Ultra high resolution crystal structure of tem-1 | x-ray diffraction | A | — | — |
| 1M40 | Ultra high resolution crystal structure of tem-1 | x-ray diffraction | A | — | — |
| 1NXY | Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (SM2) | x-ray diffraction | A | — | — |
| 1NXY | Crystal structure of the complex between M182T mutant of tem-1 and a boronic acid inhibitor (SM2) | x-ray diffraction | A | — | — |
| 1NY0 | Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (NBF) | x-ray diffraction | A | — | — |
| 1NY0 | Crystal structure of the complex between M182T mutant of tem-1 and a boronic acid inhibitor (nbf) | x-ray diffraction | A | — | — |
| 1NYM | Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (CXB) | x-ray diffraction | A | — | — |
| 1NYM | Crystal structure of the complex between M182T mutant of tem-1 and a boronic acid inhibitor (cxb) | x-ray diffraction | A | — | — |
| 1NYY | Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (105) | x-ray diffraction | A | — | — |
| 1NYY | Crystal structure of the complex between M182T mutant of tem-1 and a boronic acid inhibitor (105) | x-ray diffraction | A | — | — |
| 1PZO | TEM-1 Beta-Lactamase in Complex with a Novel, Core-Disrupting, Allosteric Inhibitor | x-ray diffraction | A | — | — |
| 1PZO | Tem-1 beta-lactamase in complex with a novel, core-disrupting, allosteric inhibitor | x-ray diffraction | A | — | — |
| 1PZP | TEM-1 Beta-Lactamase in Complex with a Novel, Core-Disrupting, Allosteric Inhibitor | x-ray diffraction | A | — | — |
| 1PZP | Tem-1 beta-lactamase in complex with a novel, core-disrupting, allosteric inhibitor | x-ray diffraction | A | — | — |
| 1TEM | 6 alpha hydroxymethyl penicilloic acid acylated on the tem-1 beta-lactamase from escherichia COLI | x-ray diffraction | A | — | — |
| 1TEM | 6 alpha hydroxymethyl penicilloic acid acylated on the tem- 1 beta-lactamase from escherichia COLI | x-ray diffraction | A | — | — |
| 1XPB | Structure of beta-lactamase TEM1 | x-ray diffraction | A | — | — |
| 1XPB | Structure of beta-lactamase TEM1 | x-ray diffraction | A | — | — |
| 1XXM | The modular architecture of protein-protein binding site | x-ray diffraction | A, B | — | — |
| 1XXM | The modular architecture of protein-protein binding site | x-ray diffraction | A, B | — | — |
| 1YT4 | Crystal structure of TEM-76 beta-lactamase at 1.4 Angstrom resolution | x-ray diffraction | A | — | — |
| 1YT4 | Crystal structure of tem-76 beta-lactamase at 1.4 ångström resolution | x-ray diffraction | A | — | — |
| 1ZG4 | TEM1 beta lactamase | x-ray diffraction | A | — | — |
| 1ZG4 | TEM1 beta lactamase | x-ray diffraction | A | — | — |
66 records more on the page itself.
Ligands
Experiment against prediction
- 8DDZ chain C against the predicted model P62593: TM-score 1.00, RMSD 0.25 Å
- 8DDZ chain D against the predicted model P62593: TM-score 1.00, RMSD 0.26 Å
- 8DDZ chain B against the predicted model P62593: TM-score 1.00, RMSD 0.27 Å
- 8DDZ chain A against the predicted model P62593: TM-score 1.00, RMSD 0.30 Å
- 1JTD chain A against the predicted model P62593: TM-score 1.00, RMSD 0.31 Å
- 1JTD chain A against the predicted model P62593: TM-score 1.00, RMSD 0.31 Å
- 5HVI chain B against the predicted model P62593: TM-score 1.00, RMSD 0.46 Å
- 5HVI chain B against the predicted model P62593: TM-score 1.00, RMSD 0.46 Å
- 5HVI chain A against the predicted model P62593: TM-score 1.00, RMSD 0.46 Å
- 5HVI chain A against the predicted model P62593: TM-score 1.00, RMSD 0.46 Å
Elsewhere
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