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Ligand · ALP

ALP · 2-(1-carboxy-2-hydroxy-ethyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid

ALP, 2-(1-carboxy-2-hydroxy-ethyl)-5,5-dimethyl-thiazolidine-4-carboxylic acid (C9 H15 N O5 S, 249.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
ALP
Formula
C9 H15 N O5 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

ALP in 4 structures; the first of them:

  • 1TEM · 6 alpha hydroxymethyl penicilloic acid acylated on the tem-1 beta-lactamase from… · ALP A291 · binds MET69, SER70, LYS73, TYR105, SER130, ASN132, GLU166, ASN170 and 6 more
  • 4Y0U · Crystal Structure of 6Alpha-Hydroxymethylpenicillanate Complexed with OXA-58, a… · ALP A301 · binds ALA82, SER83, KCX86, PHE114, TRP117, SER130, VAL132, LEU170 and 7 more
  • 1TEM · 6 alpha hydroxymethyl penicilloic acid acylated on the tem- 1 beta-lactamase from… · ALP A291 · binds MET69, SER70, LYS73, TYR105, SER130, ASN132, GLU166, ASN170 and 6 more
  • 4Y0U · Crystal structure of 6ALPHA-hydroxymethylpenicillanate complexed with oxa-58, a… · ALP A301 · binds ALA82, SER83, KCX86, PHE114, TRP117, SER130, VAL132, LEU170 and 7 more

Residues it binds most

SER 10, TRP 8, ALA 10, ARG 10, GLY 10, MET 10, VAL 10, ILE 8, KCX 8, LEU 8 (residue and the binding sites it lines).

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