UniProt P61587
Rho-related GTP-binding protein RhoE (P61587)
Rho-related GTP-binding protein RhoE (UniProt P61587): 11 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P61587
- Protein
- Rho-related GTP-binding protein RhoE
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 4 · 3 records with a druggable one
Structures
12 records of P61587 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1M7B | Crystal structure of Rnd3/RhoE: functional implications | x-ray diffraction | A | — | — |
| 1M7B | Crystal structure of RND3/RHOE: functional implications | x-ray diffraction | A | — | — |
| 2V55 | Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure | x-ray diffraction | B, D | — | — |
| 2V55 | Mechanism of multi-site phosphorylation from a rock-I:RHOE complex structure | x-ray diffraction | B, D | — | — |
| 4BG6 | 14-3-3 interaction with Rnd3 prenyl-phosphorylation motif | x-ray diffraction | Q, R | — | — |
| 4BG6 | 14-3-3 interaction with RND3 prenyl-phosphorylation motif | x-ray diffraction | Q, R | — | — |
| 7OBC | Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3 peptide | x-ray diffraction | B | FAR | 2 (best 0.53) |
| 7OBC | Crystal structure of 14-3-3 sigma in complex with phosphorylated and farnesylated RND3 peptide | x-ray diffraction | B | FAR | — |
| 7OBD | Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3 peptide and… | x-ray diffraction | B | FSC, FAR | 1 (best 0.54) |
| 7OBD | Crystal structure of 14-3-3 sigma in complex with phosphorylated and farnesylated RND3 peptide and… | x-ray diffraction | B | FSC, FAR | — |
| 8B2K | Ternary structure of 14-3-3s, RND3 phosphopeptide and dual-reactive compound 10 | x-ray diffraction | B | OQ3 | — |
| P61587 | AlphaFold monomer V2.0 prediction for rho-related GTP-binding protein rhoe (P61587) | predicted | A | — | 1 (best 0.51) |
Ligands
Experiment against prediction
- 1M7B chain A against the predicted model P61587: TM-score 0.99, RMSD 0.43 Å
- 1M7B chain A against the predicted model P61587: TM-score 0.99, RMSD 0.43 Å
- 2V55 chain B against the predicted model P61587: TM-score 0.99, RMSD 0.63 Å
- 2V55 chain B against the predicted model P61587: TM-score 0.99, RMSD 0.63 Å
- 2V55 chain D against the predicted model P61587: TM-score 0.98, RMSD 0.71 Å
- 2V55 chain D against the predicted model P61587: TM-score 0.98, RMSD 0.71 Å
- 7OBD chain B against the predicted model P61587: TM-score 0.64, RMSD 0.84 Å
- 7OBD chain B against the predicted model P61587: TM-score 0.64, RMSD 0.84 Å
- 7OBC chain B against the predicted model P61587: TM-score 0.60, RMSD 1.40 Å
- 7OBC chain B against the predicted model P61587: TM-score 0.60, RMSD 1.40 Å
Elsewhere
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