UniProt P61278
Somatostatin-14 (P61278)
Somatostatin-14 (UniProt P61278): 10 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P61278
- Protein
- Somatostatin-14
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 14 · 4 records with a druggable one
Structures
11 records of P61278 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2MI1 | Somatostatin-14 solution structure in 5% D-mannitol | solution nmr | A | — | — |
| 2MI1 | Somatostatin-14 solution structure in 5% D-mannitol | solution nmr | A | — | — |
| 7T10 | CryoEM structure of somatostatin receptor 2 in complex with somatostatin-14 and Gi3 | electron microscopy | P | — | 2 (best 0.68) |
| 7T10 | Cryoem structure of somatostatin receptor 2 in complex with somatostatin-14 and GI3 | electron microscopy | P | — | 2 (best 0.68) |
| 7XAT | Structure of somatostatin receptor 2 bound with SST14. | electron microscopy | F | — | 2 (best 0.50) |
| 7XAT | Structure of somatostatin receptor 2 bound with SST14. | electron microscopy | F | — | 2 (best 0.50) |
| 7XMR | CryoEM structure of the somatostatin receptor 2 (SSTR2) in complex with Gi1 and its endogeneous… | electron microscopy | L | — | 1 (best 0.26) |
| 7XMR | Cryoem structure of the somatostatin receptor 2 (SSTR2) in complex with GI1 and its endogeneous… | electron microscopy | L | — | 1 (best 0.26) |
| 7XMS | CryoEM structure of somatostatin receptor 4 (SSTR4) in complex with Gi1 and its endogeneous ligand… | electron microscopy | L | — | 2 (best 0.74) |
| 7XMS | Cryoem structure of somatostatin receptor 4 (SSTR4) in complex with GI1 and its endogeneous ligand… | electron microscopy | L | — | 2 (best 0.74) |
| P61278 | AlphaFold monomer V2.0 prediction for somatostatin (P61278) | predicted | A | — | — |
Experiment against prediction
- 7XAT chain F against the predicted model P61278: TM-score 0.33, RMSD 1.97 Å
- 7XAT chain F against the predicted model P61278: TM-score 0.33, RMSD 1.97 Å
- 7T10 chain P against the predicted model P61278: TM-score 0.28, RMSD 1.11 Å
- 7T10 chain P against the predicted model P61278: TM-score 0.28, RMSD 1.11 Å
- 7XMS chain L against the predicted model P61278: TM-score 0.22, RMSD 2.26 Å
- 7XMS chain L against the predicted model P61278: TM-score 0.22, RMSD 2.26 Å
- 7XMR chain L against the predicted model P61278: TM-score 0.20, RMSD 1.15 Å
- 7XMR chain L against the predicted model P61278: TM-score 0.20, RMSD 1.15 Å
- 2MI1 chain A against the predicted model P61278: TM-score 0.20, RMSD 1.79 Å
- 2MI1 chain A against the predicted model P61278: TM-score 0.20, RMSD 1.79 Å
Elsewhere
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