UniProt P61218
DNA-directed RNA polymerases I, II, and III subunit RPABC2 (P61218)
DNA-directed RNA polymerases I, II, and III subunit RPABC2 (UniProt P61218): 44 experimental structures on GenesisL1, 24 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P61218
- Protein
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- Experimental structures
- 44
- Predicted models
- 0
- Pockets
- 24 · 11 records with a druggable one
Structures
44 records of P61218 in the MolNFT archive: 44 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IY6 | Human holo-PIC in the closed state | electron microscopy | F | — | 3 (best 0.88) |
| 5IY6 | Human holo-pic in the closed state | electron microscopy | F | — | — |
| 5IY7 | Human holo-pic in the open state | electron microscopy | F | — | — |
| 5IY8 | Human holo-pic in the initial transcribing state | electron microscopy | F | — | — |
| 5IY9 | Human holo-PIC in the initial transcribing state (no IIS) | electron microscopy | F | — | — |
| 5IY9 | Human holo-pic in the initial transcribing state (no iis) | electron microscopy | F | — | — |
| 5IYA | Human core-PIC in the closed state | electron microscopy | F | — | — |
| 5IYA | Human core-pic in the closed state | electron microscopy | F | — | — |
| 5IYB | Human core-PIC in the open state | electron microscopy | F | — | 2 (best 0.80) |
| 5IYB | Human core-pic in the open state | electron microscopy | F | — | — |
| 5IYC | Human core-PIC in the initial transcribing state | electron microscopy | F | — | 2 (best 0.82) |
| 5IYC | Human core-pic in the initial transcribing state | electron microscopy | F | — | — |
| 5IYD | Human core-PIC in the initial transcribing state (no IIS) | electron microscopy | F | — | — |
| 5IYD | Human core-pic in the initial transcribing state (no iis) | electron microscopy | F | — | — |
| 6DRD | RNA pol II(G) | electron microscopy | F | — | — |
| 6O9L | Human holo-pic in the closed state | electron microscopy | F | — | — |
| 6XRE | Structure of the P53/RNA polymerase II assembly | electron microscopy | F | — | — |
| 7A6H | Cryo-EM structure of human apo RNA polymerase III | electron microscopy | F | — | — |
| 7AE1 | Cryo-EM structure of human RNA Polymerase III elongation complex 1 | electron microscopy | F | — | 2 (best 0.80) |
| 7AE1 | Cryo-EM structure of human RNA polymerase III elongation complex 1 | electron microscopy | F | — | — |
| 7AE3 | Cryo-EM structure of human RNA Polymerase III elongation complex 3 | electron microscopy | F | — | 2 (best 0.80) |
| 7AE3 | Cryo-EM structure of human RNA polymerase III elongation complex 3 | electron microscopy | F | — | — |
| 7AEA | Cryo-EM structure of human RNA Polymerase III elongation complex 2 | electron microscopy | F | — | 2 (best 0.81) |
| 7AEA | Cryo-EM structure of human RNA polymerase III elongation complex 2 | electron microscopy | F | — | — |
| 7AST | Apo human RNA polymerase III | electron microscopy | E | — | — |
| 7D58 | Cryo-EM structure of human RNA polymerase III in elongating state | electron microscopy | F | — | — |
| 7D59 | Cryo-EM structure of human RNA polymerase III in apo state | electron microscopy | F | — | — |
| 7DN3 | Structure of human RNA polymerase III elongation complex | electron microscopy | F | — | — |
| 7DTH | Solution structure of RPB6, common subunit of RNA polymerases I, II, and III | solution nmr | A | — | — |
| 7DTI | Solution structure of the complex between RNA polymerase subunit RPB6 and tfiih P62 pH domain | solution nmr | A | — | — |
| 7DU2 | RNA polymerase III ec complex in post-translocation state | electron microscopy | F | — | — |
| 7FJI | human Pol III elongation complex | electron microscopy | F | — | 2 (best 0.80) |
| 7FJI | Human pol III elongation complex | electron microscopy | F | — | — |
| 7FJJ | Human pol III pre-termination complex | electron microscopy | F | — | — |
| 7OB9 | Cryo-EM structure of human RNA Polymerase I in elongation state | electron microscopy | F | — | 3 (best 0.81) |
| 7OB9 | Cryo-EM structure of human RNA polymerase I in elongation state | electron microscopy | F | — | — |
| 7OBA | Cryo-EM structure of human RNA polymerase I in complex with RRN3 | electron microscopy | F | — | — |
| 7OBB | Cryo-EM structure of human RNA polymerase I open complex | electron microscopy | F | — | — |
| 7VBA | Structure of the pre state human RNA Polymerase I Elongation Complex | electron microscopy | F | — | — |
| 8A43 | Human RNA polymerase I | electron microscopy | F | — | 2 (best 0.87) |
| 8A43 | Human RNA polymerase I | electron microscopy | F | — | — |
| 8ITY | human RNA polymerase III pre-initiation complex closed DNA 1 | electron microscopy | F | — | 2 (best 0.82) |
| 8IUE | RNA polymerase III pre-initiation complex melting complex 1 | electron microscopy | F | — | 2 (best 0.79) |
| P61218 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I, II, and III subunit RPABC2… | — | — | — |
Elsewhere
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