UniProt P55884
Eukaryotic translation initiation factor 3 subunit B (P55884)
Eukaryotic translation initiation factor 3 subunit B (UniProt P55884): 16 experimental structures and 1 predicted model on GenesisL1, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P55884
- Protein
- Eukaryotic translation initiation factor 3 subunit B
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 17 · 6 records with a druggable one
Structures
17 records of P55884 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2KRB | Solution structure of EIF3B-RRM bound to EIF3J peptide | solution nmr | A | — | — |
| 2KRB | Solution structure of EIF3B-rrm bound to EIF3J peptide | solution nmr | A | — | — |
| 2NLW | Solution structure of the RRM domain of human eukaryotic initiation factor 3b | solution nmr | A | — | — |
| 2NLW | Solution structure of the rrm domain of human eukaryotic initiation factor 3B | solution nmr | A | — | — |
| 5K1H | eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex.… | electron microscopy | B | — | 5 (best 0.63) |
| 5K1H | EIF3B relocated to the intersubunit face to interact with EIF1 and below the EIF2 ternary-complex.… | electron microscopy | B | — | — |
| 6YBT | Structure of a human 48S translational initiation complex - eIF3bgi | electron microscopy | 1 | — | 8 (best 0.74) |
| 6YBT | Structure of a human 48S translational initiation complex - EIF3BGI | electron microscopy | 1 | — | — |
| 6ZON | SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1 | electron microscopy | B | — | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | B | — | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | 1 | — | 1 (best 0.86) |
| 7QP7 | Structure of the human 48S initiation complex in closed state (h48S AUG closed) | electron microscopy | 1 | — | — |
| 8OZ0 | Structure of a human 48S translation initiation complex with eIF4F and eIF4A | electron microscopy | I | — | 1 (best 0.86) |
| 8PJ1 | Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | electron microscopy | 1 | — | — |
| 8PJ6 | Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3… | electron microscopy | 1 | — | 1 (best 0.85) |
| 8XXN | Cryo-EM structure of the human 43S ribosome with PDCD4 | electron microscopy | 3B | — | 1 (best 0.82) |
| P55884 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 3 subunit B (P55884) | predicted | A | — | — |
Experiment against prediction
- 7QP7 chain 1 against the predicted model P55884: TM-score 0.92, RMSD 2.34 Å
- 8OZ0 chain I against the predicted model P55884: TM-score 0.92, RMSD 2.80 Å
- 7QP6 chain 1 against the predicted model P55884: TM-score 0.89, RMSD 2.69 Å
- 6YBT chain 1 against the predicted model P55884: TM-score 0.85, RMSD 3.71 Å
- 6YBT chain 1 against the predicted model P55884: TM-score 0.85, RMSD 3.71 Å
- 6ZON chain B against the predicted model P55884: TM-score 0.84, RMSD 3.27 Å
- 7A09 chain B against the predicted model P55884: TM-score 0.83, RMSD 3.43 Å
- 8XXN chain 3B against the predicted model P55884: TM-score 0.82, RMSD 3.17 Å
- 8PJ1 chain 1 against the predicted model P55884: TM-score 0.81, RMSD 4.29 Å
- 2KRB chain A against the predicted model P55884: TM-score 0.80, RMSD 1.86 Å
Elsewhere
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