UniProt P55011
Solute carrier family 12 member 2 (P55011)
Solute carrier family 12 member 2 (UniProt P55011): 11 experimental structures on GenesisL1, 8 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P55011
- Protein
- Solute carrier family 12 member 2
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 60 · 3 records with a druggable one
Structures
11 records of P55011 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6PZT | cryo-EM structure of human NKCC1 | electron microscopy | B, A | — | — |
| 6PZT | Cryo-EM structure of human NKCC1 | electron microscopy | B, A | — | — |
| 7D10 | HUMAN NKCC1 | electron microscopy | A, B | PLM | — |
| 7MXO | CryoEM structure of human NKCC1 | electron microscopy | A, B | CL, K | 20 (best 0.87) |
| 7N3N | CryoEM structure of human NKCC1 state Fu-I | electron microscopy | A, B | FUN | 20 (best 0.84) |
| 7S1X | Cryo-EM structure of human NKCC1 K289NA492EL671C bound with bumetanide | electron microscopy | B, A | K, CL | — |
| 7S1Y | Cryo-EM structure of human NKCC1 K289NA492E bound with bumetanide | electron microscopy | A, B | K, CL | — |
| 7S1Z | Cryo-EM structure of human NKCC1 K289NA492EL671C | electron microscopy | A, B | — | — |
| 7SMP | CryoEM structure of NKCC1 Bu-I | electron microscopy | B, A | 82U, K | 20 (best 0.76) |
| 7ZGO | Cryo-EM structure of human NKCC1 (TM domain) | electron microscopy | A, B | NA, K, CL, POV, Y01 | — |
| P55011 | AlphaFold monomer V2.0 prediction for solute carrier family 12 member 2 (P55011) | — | — | — |
Ligands
- K · Potassium ion · in 5 records
- CL · Chloride ion · in 4 records
- 82U · 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid · in 1 record
- FUN · 5-(aminosulfonyl)-4-chloro-2-[(2-furylmethyl) amino]benzoic acid · in 1 record
- NA · Sodium ion · in 1 record
- PLM · Palmitic acid · in 1 record
- POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · in 1 record
- Y01 · Cholesterol hemisuccinate · in 1 record
Elsewhere
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