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UniProt P52848

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (P52848)

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (UniProt P52848), EC 2.8.2.8, 3.5.1.-: 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 29 pockets. Binding sites, druggability and…

UniProt
P52848
Protein
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
EC
2.8.2.8, 3.5.1.-
Experimental structures
5
Predicted models
1
Ligands
2
Pockets
29 · 4 records with a druggable one

Structures

6 records of P52848 in the MolNFT archive: 5 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
1NSTThe sulfotransferase domain of human haparin sulfate N-DEACETYLASE/N-sulfotransferasex-ray diffractionA——
1NSTThe sulfotransferase domain of human haparin sulfate N-DEACETYLASE/N- sulfotransferasex-ray diffractionA——
8CCYHuman heparan sulfate N-deacetylase-N-sulfotransferase 1 in complex with calcium and…electron microscopyAA3P, CA6 (best 0.73)
8CD0Human heparan sulfate N-deacetylase-N-sulfotransferase 1 in complex with calcium…electron microscopyAA3P, CA7 (best 0.75)
8CHSHuman heparan sulfate N-deacetylase-N-sulfotransferase 1 in complex with calcium…electron microscopyAA3P, CA6 (best 0.76)
P52848AlphaFold monomer V2.0 prediction for bifunctional heparan sulfate N-DEACETYLASE/N-sulfotransferase…predictedA—10 (best 0.73)

Ligands

  • A3P · Adenosine-3'-5'-diphosphate · in 3 records
  • CA · Calcium ion · in 3 records

Experiment against prediction

Elsewhere

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