UniProt P52434

DNA-directed RNA polymerases I, II, and III subunit RPABC3 (P52434)

DNA-directed RNA polymerases I, II, and III subunit RPABC3 (UniProt P52434): 57 experimental structures on GenesisL1, 45 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: P52434
Protein: DNA-directed RNA polymerases I, II, and III subunit RPABC3
Experimental structures: 57
Predicted models: 0
Pockets: 45 · 24 records with a druggable one

Structures

57 records of P52434 in the MolNFT archive: 57 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
2F3I	Solution Structure of a Subunit of RNA Polymerase II	solution nmr	A	—	—
2F3I	Solution structure of a subunit of RNA polymerase II	solution nmr	A	—	—
5IY6	Human holo-PIC in the closed state	electron microscopy	H	—	1 (best 0.79)
5IY6	Human holo-pic in the closed state	electron microscopy	H	—	—
5IY7	Human holo-PIC in the open state	electron microscopy	H	—	1 (best 0.88)
5IY7	Human holo-pic in the open state	electron microscopy	H	—	—
5IY8	Human holo-PIC in the initial transcribing state	electron microscopy	H	—	1 (best 0.89)
5IY8	Human holo-pic in the initial transcribing state	electron microscopy	H	—	—
5IY9	Human holo-PIC in the initial transcribing state (no IIS)	electron microscopy	H	—	—
5IY9	Human holo-pic in the initial transcribing state (no iis)	electron microscopy	H	—	—
5IYA	Human core-PIC in the closed state	electron microscopy	H	—	—
5IYA	Human core-pic in the closed state	electron microscopy	H	—	—
5IYB	Human core-PIC in the open state	electron microscopy	H	—	1 (best 0.86)
5IYB	Human core-pic in the open state	electron microscopy	H	—	—
5IYC	Human core-PIC in the initial transcribing state	electron microscopy	H	—	1 (best 0.89)
5IYC	Human core-pic in the initial transcribing state	electron microscopy	H	—	—
5IYD	Human core-PIC in the initial transcribing state (no IIS)	electron microscopy	H	—	—
5IYD	Human core-pic in the initial transcribing state (no iis)	electron microscopy	H	—	—
6DRD	RNA Pol II(G)	electron microscopy	H	—	5 (best 0.87)
6DRD	RNA pol II(G)	electron microscopy	H	—	—
6O9L	Human holo-pic in the closed state	electron microscopy	H	—	—
6XRE	Structure of the P53/RNA polymerase II assembly	electron microscopy	H	—	—
7A6H	Cryo-EM structure of human apo RNA polymerase III	electron microscopy	H	—	—
7AE1	Cryo-EM structure of human RNA Polymerase III elongation complex 1	electron microscopy	H	—	2 (best 0.81)
7AE1	Cryo-EM structure of human RNA polymerase III elongation complex 1	electron microscopy	H	—	—
7AE3	Cryo-EM structure of human RNA Polymerase III elongation complex 3	electron microscopy	H	—	2 (best 0.82)
7AE3	Cryo-EM structure of human RNA polymerase III elongation complex 3	electron microscopy	H	—	—
7AEA	Cryo-EM structure of human RNA Polymerase III elongation complex 2	electron microscopy	H	—	2 (best 0.80)
7AEA	Cryo-EM structure of human RNA polymerase III elongation complex 2	electron microscopy	H	—	—
7AST	Apo Human RNA Polymerase III	electron microscopy	D	—	3 (best 0.81)
7AST	Apo human RNA polymerase III	electron microscopy	D	—	—
7D58	cryo-EM structure of human RNA polymerase III in elongating state	electron microscopy	H	—	3 (best 0.89)
7D58	Cryo-EM structure of human RNA polymerase III in elongating state	electron microscopy	H	—	—
7D59	cryo-EM structure of human RNA polymerase III in apo state	electron microscopy	H	—	2 (best 0.84)
7D59	Cryo-EM structure of human RNA polymerase III in apo state	electron microscopy	H	—	—
7DN3	Structure of Human RNA Polymerase III elongation complex	electron microscopy	H	—	2 (best 0.82)
7DN3	Structure of human RNA polymerase III elongation complex	electron microscopy	H	—	—
7DU2	RNA polymerase III ec complex in post-translocation state	electron microscopy	H	—	—
7FJI	human Pol III elongation complex	electron microscopy	H	—	2 (best 0.83)
7FJI	Human pol III elongation complex	electron microscopy	H	—	—
7FJJ	human Pol III pre-termination complex	electron microscopy	H	—	2 (best 0.81)
7FJJ	Human pol III pre-termination complex	electron microscopy	H	—	—
7OB9	Cryo-EM structure of human RNA Polymerase I in elongation state	electron microscopy	H	—	1 (best 0.75)
7OB9	Cryo-EM structure of human RNA polymerase I in elongation state	electron microscopy	H	—	—
7OBA	Cryo-EM structure of human RNA Polymerase I in complex with RRN3	electron microscopy	H	—	2 (best 0.74)
7OBA	Cryo-EM structure of human RNA polymerase I in complex with RRN3	electron microscopy	H	—	—
7OBB	Cryo-EM structure of human RNA Polymerase I Open Complex	electron microscopy	H	—	2 (best 0.74)
7OBB	Cryo-EM structure of human RNA polymerase I open complex	electron microscopy	H	—	—
7VBA	Structure of the pre state human RNA Polymerase I Elongation Complex	electron microscopy	H	—	—
7VBB	Structure of the post state human RNA Polymerase I Elongation Complex	electron microscopy	H	—	2 (best 0.74)
7VBC	Back track state of human RNA Polymerase I Elongation Complex	electron microscopy	H	—	2 (best 0.73)
8A43	Human RNA polymerase I	electron microscopy	H	—	2 (best 0.76)
8A43	Human RNA polymerase I	electron microscopy	H	—	—
8ITY	human RNA polymerase III pre-initiation complex closed DNA 1	electron microscopy	H	—	2 (best 0.81)
8IUE	RNA polymerase III pre-initiation complex melting complex 1	electron microscopy	H	—	1 (best 0.83)
8IUH	RNA polymerase III pre-initiation complex open complex 1	electron microscopy	H	—	1 (best 0.82)
P52434	AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I, II, and III subunit RPABC3…	—		—	—

Elsewhere

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