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UniProt P52298

Nuclear cap-binding protein subunit 2 (P52298)

Nuclear cap-binding protein subunit 2 (UniProt P52298): 25 experimental structures on GenesisL1, 4 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P52298
Protein
Nuclear cap-binding protein subunit 2
Experimental structures
25
Predicted models
0
Ligands
4
Pockets
15 · 2 records with a druggable one

Structures

25 records of P52298 in the MolNFT archive: 25 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1H2TStructure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppGx-ray diffractionZ——
1H2TStructure of the human nuclear cap-binding-complex (cbc) in complex with a cap analogue M7GPPPGx-ray diffractionZ——
1H2UStructure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppGx-ray diffractionX, Y——
1H2UStructure of the human nuclear cap-binding-complex (cbc) in complex with a cap analogue M7GPPPGx-ray diffractionX, Y——
1H2VStructure of the human nuclear cap-binding-complex (CBC)x-ray diffractionZ——
1H2VStructure of the human nuclear cap-binding-complex (cbc)x-ray diffractionZ——
1H6Knuclear Cap Binding Complexx-ray diffractionX, Y, Z——
1H6KNuclear cap binding complexx-ray diffractionX, Y, Z——
1N52Cap Binding Complexx-ray diffractionB——
1N52Cap binding complexx-ray diffractionB——
1N54Cap Binding Complex m7GpppG freex-ray diffractionB——
1N54Cap binding complex M7GPPPG freex-ray diffractionB——
3FEXCrystal structure of the CBC-importin alpha complex.x-ray diffractionB——
3FEXCrystal structure of the cbc-importin alpha complex.x-ray diffractionB——
3FEYCrystal structure of the CBC-importin alpha complex.x-ray diffractionB——
3FEYCrystal structure of the cbc-importin alpha complex.x-ray diffractionB——
5OO6Complex of human nuclear cap-binding complex with ARS2 C-terminal peptidex-ray diffractionB, E, H, K, N, Q, T, WMGT—
5OO6Complex of human nuclear cap-binding complex with ARS2 C-terminal peptidex-ray diffractionB, E, H, K, N, Q, T, WMGT—
5OOBComplex of human nuclear cap-binding complex with M7GTP and nelf-E C-terminal peptidex-ray diffractionB, D, G, JMGT—
5OOBComplex of human nuclear cap-binding complex with M7GTP and nelf-E C- terminal peptidex-ray diffractionB, D, G, JMGT—
6D0YX-ray Crystal Structure of PGC-1beta C-terminus bound to the CBP80-CBP20 Cap Binding Complexx-ray diffractionAGTA7 (best 0.78)
6D0YX-ray crystal structure of pgc-1BETA C-terminus bound to the CBP80- CBP20 cap binding complexx-ray diffractionAGTA—
7ABGHuman pre-Bact-1 spliceosomeelectron microscopyA1GTG—
8SUYCryo-EM structure of the human cap binding complex (CBC)electron microscopyBM7G8 (best 0.77)
P52298AlphaFold monomer V2.0 prediction for nuclear cap-binding protein subunit 2 (P52298)———

Ligands

  • MGT · 7N-methyl-8-hydroguanosine-5'-triphosphate · in 4 records
  • GTA · P1-7-methylguanosine-P3-adenosine-5',5'-triphosphate · in 2 records
  • GTG · 7-methyl-guanosine-5'-triphosphate-5'-guanosine · in 1 record
  • M7G · 7N-methyl-8-hydroguanosine-5'-diphosphate · in 1 record

Elsewhere

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