UniProt P50667
Cytochrome c oxidase subunit 2 (P50667)
Cytochrome c oxidase subunit 2 (UniProt P50667), EC 7.1.1.9: 1 experimental structure and 1 predicted model on GenesisL1, 6 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P50667
- Protein
- Cytochrome c oxidase subunit 2
- EC
- 7.1.1.9
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 1 · 1 record with a druggable one
Structures
2 records of P50667 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8UGI | High resolution in-situ structure of typeA supercomplex in respiratory chain (I1III2IV1,composite) | electron microscopy | 4B | PGV, HEA, MG, CDL, CUA, PSC | 1 (best 0.91) |
| P50667 | AlphaFold monomer V2.0 prediction for cytochrome C oxidase subunit 2 (P50667) | predicted | A | — | — |
Ligands
- CDL · Cardiolipin · in 1 record
- CUA · Dinuclear copper ion · in 1 record
- HEA · Heme-A · in 1 record
- MG · Magnesium ion · in 1 record
- PGV · (1R)-2-{[{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11E)-octadec-11-enoate · in 1 record
- PSC · (7R,17E,20E)-4-hydroxy-N,N,N-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide · in 1 record
Experiment against prediction
- 8UGI chain 4B against the predicted model P50667: TM-score 0.99, RMSD 0.58 Å
Elsewhere
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