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UniProt P50405

Pulmonary surfactant-associated protein B (P50405)

Pulmonary surfactant-associated protein B (UniProt P50405): 7 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…

UniProt
P50405
Protein
Pulmonary surfactant-associated protein B
Experimental structures
7
Predicted models
1
Ligands
4
Pockets
2 · 0 records with a druggable one

Structures

8 records of P50405 in the MolNFT archive: 7 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6VYNN-terminal domain of mouse surfactant protein B with bound lipid, wild typex-ray diffractionA, B, C, D, F, H, E, GRXY—
6VZ0C-terminal domain of mouse surfactant protein B crystallized at high pHx-ray diffractionA, BZN—
6VZDN-terminal domain of mouse surfactant protein B (K46E/R51E mutant) with bound lipidx-ray diffractionA, E, B, CRXY—
6VZEC-terminal domain of mouse surfactant protein B crystallized at low pHx-ray diffractionB, E, H, D, F, G, C, ASO4—
6VZEC-terminal domain of mouse surfactant protein B crystallized at low pHx-ray diffractionB, E, H, D, F, G, C, ASO4—
6W1BN-terminal domain of mouse surfactant protein B with bound lipid, Y59A/H79A mutantx-ray diffractionA, E, B, C, D, F, G, HPEE—
7MBKN-terminal domain of mouse surfactant protein B, 6W mutantx-ray diffractionB, A——
P50405AlphaFold monomer V2.0 prediction for pulmonary surfactant-associated protein B (P50405)predictedA—2 (best 0.39)

Ligands

  • RXY · (7Z,19R,22R)-25-amino-22-hydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphapentacos-7-en-19-yl (9Z)-octadec-9-enoate · in 2 records
  • SO4 · Sulfate ion · in 2 records
  • PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · in 1 record
  • ZN · Zinc ion · in 1 record

Experiment against prediction

Elsewhere

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