UniProt P50052
Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562 (P50052)
Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562 (UniProt P50052): 14 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, druggability and…
- UniProt
- P50052
- Protein
- Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 26 · 4 records with a druggable one
Structures
15 records of P50052 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UNF | XFEL structure of human angiotensin II type 2 receptor (Monoclinic form) in complex with compound 1… | x-ray diffraction | A, B | 8ES | 11 (best 0.85) |
| 5UNF | Xfel structure of human angiotensin II type 2 receptor (monoclinic form) in complex with compound 1… | x-ray diffraction | A, B | 8ES | — |
| 5UNG | XFEL structure of human angiotensin II type 2 receptor (Orthorhombic form) in complex with compound… | x-ray diffraction | B | 8ES, OLA | — |
| 5UNG | Xfel structure of human angiotensin II type 2 receptor (orthorhombic form) in complex with compound… | x-ray diffraction | B | 8ES, OLA | — |
| 5UNH | Synchrotron structure of human angiotensin II type 2 receptor in complex with compound 2… | x-ray diffraction | A, B | 8EM | — |
| 5UNH | Synchrotron structure of human angiotensin II type 2 receptor in complex with compound 2… | x-ray diffraction | A, B | 8EM | — |
| 5XJM | Complex structure of angiotensin II type 2 receptor with Fab | x-ray diffraction | A | — | 6 (best 0.70) |
| 5XJM | Complex structure of angiotensin II type 2 receptor with Fab | x-ray diffraction | A | — | — |
| 6JOD | Angiotensin II type 2 receptor with ligand | x-ray diffraction | A | — | 4 (best 0.75) |
| 6JOD | Angiotensin II type 2 receptor with ligand | x-ray diffraction | A | — | — |
| 7C6A | Crystal structure of AT2R-BRIL and SRP2070_Fab complex | x-ray diffraction | A | — | 5 (best 0.54) |
| 7C6A | Crystal structure of AT2R-bril and SRP2070_FAB complex | x-ray diffraction | A | — | — |
| 7JNI | Crystal structure of the angiotensin II type 2 receptoror (AT2R) in complex with EMA401 | x-ray diffraction | A, B | OLA | — |
| 7JNI | Crystal structure of the angiotensin II type 2 receptoror (AT2R) in complex with EMA401 | x-ray diffraction | A, B | OLA | — |
| P50052 | AlphaFold monomer V2.0 prediction for type-2 angiotensin II receptor (P50052) | predicted | A | — | — |
Ligands
- 8ES · N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide · in 4 records
- OLA · Oleic acid · in 4 records
- 8EM · N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide · in 2 records
Experiment against prediction
- 6JOD chain A against the predicted model P50052: TM-score 0.98, RMSD 1.14 Å
- 6JOD chain A against the predicted model P50052: TM-score 0.98, RMSD 1.14 Å
- 5UNF chain B against the predicted model P0ABE7: TM-score 0.26, RMSD 0.95 Å
- 5UNF chain B against the predicted model P0ABE7: TM-score 0.26, RMSD 0.95 Å
- 5UNH chain A against the predicted model P0ABE7: TM-score 0.27, RMSD 0.96 Å
- 5UNH chain A against the predicted model P0ABE7: TM-score 0.27, RMSD 0.96 Å
- 5UNG chain B against the predicted model P0ABE7: TM-score 0.25, RMSD 0.98 Å
- 5UNG chain B against the predicted model P0ABE7: TM-score 0.25, RMSD 0.98 Å
- 7JNI chain A against the predicted model P0ABE7: TM-score 0.26, RMSD 0.99 Å
- 7JNI chain A against the predicted model P0ABE7: TM-score 0.26, RMSD 0.99 Å
Elsewhere
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