UniProt P49789
Bis(5'-adenosyl)-triphosphatase (P49789)
Bis(5'-adenosyl)-triphosphatase (UniProt P49789), EC 3.6.1.29: 18 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P49789
- Protein
- Bis(5'-adenosyl)-triphosphatase
- EC
- 3.6.1.29
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 6 · 1 record with a druggable one
Structures
19 records of P49789 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FHI | Substrate analog (IB2) complex with the fragile histidine triad protein, fhit | x-ray diffraction | A | — | — |
| 1FHI | Substrate analog (IB2) complex with the fragile histidine triad protein, fhit | x-ray diffraction | A | — | — |
| 1FIT | Fhit (fragile histidine triad protein) | x-ray diffraction | A | — | — |
| 1FIT | Fhit (fragile histidine triad protein) | x-ray diffraction | A | — | — |
| 2FHI | Substrate analog (IB2) complex with the his 96 asn substitution of the fragile histidine triad… | x-ray diffraction | A | — | — |
| 2FHI | Substrate analog (IB2) complex with the his 96 asn substitution of the fragile histidine triad… | x-ray diffraction | A | — | — |
| 2FIT | Fhit (fragile histidine triad protein) | x-ray diffraction | A | — | — |
| 2FIT | Fhit (fragile histidine triad protein) | x-ray diffraction | A | — | — |
| 3FIT | Fhit (fragile histidine triad protein) in complex with ADENOSINE/SULFATE AMP analog | x-ray diffraction | A | — | — |
| 3FIT | Fhit (fragile histidine triad protein) in complex with ADENOSINE/SULFATE AMP analog | x-ray diffraction | A | — | — |
| 4FIT | FHIT-APO | x-ray diffraction | A | — | — |
| 4FIT | FHIT-APO | x-ray diffraction | A | — | — |
| 5FIT | Fhit-substrate analog | x-ray diffraction | A | AP2 | 1 (best 0.38) |
| 5FIT | Fhit-substrate analog | x-ray diffraction | A | — | — |
| 6FIT | Fhit-transition state analog | x-ray diffraction | A | AMW | 1 (best 0.43) |
| 6FIT | Fhit-transition state analog | x-ray diffraction | A | AMW | — |
| 7P8P | Crystal structure of Fhit covalently bound to a nucleotide | x-ray diffraction | A, B, C, D | 6BI, NA | 4 (best 0.78) |
| 7P8P | Crystal structure of fhit covalently bound to a nucleotide | x-ray diffraction | A, B, C, D | 6BI, NA | — |
| P49789 | AlphaFold monomer V2.0 prediction for BIS(5'-adenosyl)-triphosphatase (P49789) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6FIT chain A against the predicted model P49789: TM-score 0.99, RMSD 0.38 Å
- 6FIT chain A against the predicted model P49789: TM-score 0.99, RMSD 0.38 Å
- 2FHI chain A against the predicted model P49789: TM-score 0.99, RMSD 0.48 Å
- 2FHI chain A against the predicted model P49789: TM-score 0.99, RMSD 0.48 Å
- 7P8P chain D against the predicted model P49789: TM-score 0.99, RMSD 0.52 Å
- 7P8P chain D against the predicted model P49789: TM-score 0.99, RMSD 0.52 Å
- 7P8P chain C against the predicted model P49789: TM-score 0.99, RMSD 0.54 Å
- 7P8P chain C against the predicted model P49789: TM-score 0.99, RMSD 0.54 Å
- 4FIT chain A against the predicted model P49789: TM-score 0.98, RMSD 0.56 Å
- 4FIT chain A against the predicted model P49789: TM-score 0.98, RMSD 0.56 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.