MolNFT v1 · #91624 · protein

FHIT-APO

4FIT · Fragile histidine triad protein: “FHIT-APO”. X-ray diffraction, 1 pocket (best druggability 0.42). MolNFT v1 #91624 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4FIT
Type: protein
Length: 126 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fragile histidine triad protein
EC: 3.6.1.29
UniProt: P49789
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fragile histidine triad protein (EC 3.6.1.29)	protein	126	33% helix, 24% strand	P49789

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	146	0.42	0.74	23	empty

Compared structures

4FIT · FHIT-APO · the same entry in another collection · chain A against A, TM-score 1.00
P49789 · AlphaFold monomer V2.0 prediction for BIS(5'-adenosyl)-triphosphatase (P49789) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49789
Elsewhere: RCSB PDB 4FIT · PDBe 4FIT · UniProt P49789

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