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UniProt P49147

Cytosolic phospholipase A2 (P49147)

Cytosolic phospholipase A2 (UniProt P49147): 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P49147
Protein
Cytosolic phospholipase A2
Experimental structures
2
Predicted models
1
Ligands
3
Pockets
11 · 1 record with a druggable one

Structures

3 records of P49147 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6IEJThe C2 domain of cytosolic phospholipase A2 alpha bound to phosphatidylcholinex-ray diffractionA, B, CCA, MG, HXG—
6IEJThe C2 domain of cytosolic phospholipase A2 alpha bound to phosphatidylcholinex-ray diffractionA, B, CCA, MG, HXG—
P49147AlphaFold monomer V2.0 prediction for cytosolic phospholipase A2 (P49147)predictedA—11 (best 0.76)

Ligands

  • CA · Calcium ion · in 2 records
  • HXG · 1,2-dihexanoyl-sn-glycero-3-phosphocholine · in 2 records
  • MG · Magnesium ion · in 2 records

Experiment against prediction

Elsewhere

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